Purpose. To analyze the array of special literature and to summarize the information obtained regarding antiviral vaccines in aquaculture for the prevention of the most common viral diseases of fish. Findings. An overview of scientific publications devoted to the properties of various antiviral vaccines, which are used in many countries of the world, is presented. Information about commercial vaccines that are available on the world market and experimental developments that are at the stage of prototype or licensing is summarized. Attention is focused on the types of vaccines, namely inactivated, subunit and DNA vaccines, as well as on industrially important fish species for which prophylactic immunization is used. Some aspects of the immune response and the mechanism of action of experimental vaccines against the infectious pancreatic necrosis virus have been revealed. Practical Value. The review may be useful for academics, post-graduates, veterinary specialists and fish farm owners. Key words: viruses, vaccines, adjuvants, fish. REFERENCES