Purpose: to analyze possible associations between a Fantastic lifestyle and self-perception of oral health, binge drinking, and socio-demographic variables among public college students.Methods: questionnaires validated for use in Brazil were applied to 672 students in randomly selected courses. It was the first questionnaire to assess a Fantastic lifestyle, the second to measure oral health-related quality of life , and the third to include socio-demographic information. Multilevel linear regression was used for the analyses.Results: among the participants, 64.21% were full-time students, 52.82% were females, 50.85% had a family income between 4 and 8 minimum wages, 16.75% were binge drinkers, and 22.22% used to drive after drinking. Socio-demographic variables such as income (p = 0.001), religion (p = 0.02), marital status (p = 0.021), binge drinking (p <0.001), and OHIP-14 (p <0.001) were associated with a Fantastic lifestyle.Conclusions: fantastic lifestyle of the Brazilian college students was associated with income, oral health-related quality of life, marital status, religion, and alcohol consumption (binge drinking).