The value of an integrated approach for understanding the neocortex by combining functional characterization of single neuron activity with the underlying circuit architecture has been understood since the dawn of modern neuroscience. However, in practice, anatomical connectivity and physiology have been studied mostly separately. Following in the footsteps of previous studies that have combined physiology and anatomy in the same tissue, here we present a unique functional connectomics dataset that contains calcium imaging of an estimated 75,000 neurons from primary visual cortex (VISp) and three higher visual areas (VISrl, VISal and VISlm), that were recorded while a mouse viewed natural movies and parametric stimuli. The functional data were co-registered with electron microscopy (EM) data of the same volume which were automatically segmented, reconstructing more than 200,000 cells (neuronal and non-neuronal) and 524 million synapses. Subsequent proofreading of some neurons in this volume yielded reconstructions that include complete dendritic trees as well the local and inter-areal axonal projections. The largest proofread excitatory axon reached a length of 19 mm and formed 1,893 synapses, while the largest inhibitory axon formed 10,081 synapses. Here we release this dataset as an open access resource to the scientific community including a set of analysis tools that allows easy data access, both programmatically and through a web user interface.
You never reach the Body without Organs, you can't reach it, you are forever attaining it, it is a limit. People ask, So what is this BwO? - But you're already on it, scurrying like vermin, grouping like a blind person, or running like a lunatic: desert traveller and nomad of the steppes. On it we sleep, live our waking lives, fight - fight and are fought - seek our place, experience untold happiness and fabulous defeats; on it we penetrate and are penetrated; on it we love. (Deleuze and Guattari, 1987: 150)
Over 750 entriesThe most authoritative and up-to-date dictionary of critical theory available, covering the Frankfurt school, cultural materialism, cultural studies, gender studies, film studies, literary theory, hermeneutics, historical materialism, Internet studies, and sociopolitical critical theory. It explains complex theoretical discourses, such as Marxism, psychoanalysis, structuralism, deconstruction, and postmodernism clearly and provides biographies of figures who have influenced the discipline, such as Deleuze and Foucault.This new edition has been updated to extend coverage of diaspora, race, and postcolonial theory, and of queer and sexuality studies, ensuring that it remains invaluable for students of literary and cultural studies and anyone studying a humanities subject requiring a knowledge of theory.
If the development of assemblage theory does not need to be anchored in the work of Deleuze and Guattari, as increasingly seems to be the case in the social sciences, then cannot one say that the future of assemblage theory is an illusion? It is an illusion in the sense that it continues to act as though the concept was invented by Deleuze and Guattari, but because it does not feel obligated to draw on their work in its actual operation or development, it cannot lay claim to being authentic. That this does not trouble certain scholars in the social sciences is troubling to me. So in this paper I offer first of all critique of this illusory synthetic version of the assemblage and accompany that with a short case study showing what can be gained by returning to Deleuze and Guattari.
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