These data suggest that AIx might be a more sensitive marker of arterial stiffening and risk in younger individuals but aortic PWV is likely to be a better measure in older individuals.

The asynchronous relationship between millennial-scale temperature changes over Greenland and Antarctica during the last glacial period has led to the notion of a bipolar seesaw which acts to redistribute heat depending on the state of meridional overturning circulation within the Atlantic Ocean. Here we present new records from the South Atlantic that show rapid changes during the last deglaciation that were instantaneous (within dating uncertainty) and of opposite sign to those observed in the North Atlantic. Our results demonstrate a direct link between the abrupt changes associated with variations in the Atlantic meridional overturning circulation and the more gradual adjustments characteristic of the Southern Ocean. These results emphasize the importance of the Southern Ocean for the development and transmission of millennial-scale climate variability and highlight its role in deglacial climate change and the associated rise in atmospheric carbon dioxide.

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[1] The basis for, and use of, fine grain size parameters for inference of paleoflow speeds is reviewed here. The basis resides in data on deposited sediment taken in conjunction with flow speed measurements in the field, experimental data on suspended sediment transport and deposition, and theoretical treatments of the generation of size distributions of deposits from suspension controlled by particle settling velocity and flow speed. In the deep sea, sorting events occur under resuspension/deposition events in benthic storms. At flow speeds below 10-15 cm s À1 , size in the noncohesive ''sortable silt'' (10-63 mm) range is controlled by selective deposition, whereas above that range, removal of finer material by winnowing also plays a role. The best particle size instruments to measure a flow speed-related grain size employ the settling velocity method, while laser diffraction sizers can yield misleading results because of particle shape effects. Potential problems, including source effects, downslope supply on continental margins, spatial variability of flow over bedforms, and influence of ice-rafted detritus, are examined. A number of studies using the sortable silt flow speed proxy are reviewed, and inverse modeling of grain size distributions is examined. Outstanding problems are that corroboration is sparse because almost no studies have yet used the full range of proxies for flow rate and water mass identification and that the sortable silt mean size is not yet properly calibrated in terms of flow speed.