Background: Renal replacement therapy (RRT) in form of peritoneal dialysis (PD) is an important treatment procedure in Paediatric Acute Kidney Injury (AKI) management. It is cost effective and materials are easily sourced for in the developing countries. There is paucity of sub-Saharan Africa data on the use of PD in paediatric AKI, hence this study. Methods: This was a retrospective and descriptive study of cohort of children who were admitted into Emergency Paediatrics Unit of Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, and had PD done between July 1st, 2007 and July 31st, 2019. Age, gender, cause of AKI, indication for dialysis, type of dialysis fluid and peritoneal access used, duration, complication and outcome were documented. Results: A total number of 11 children who had acute PD due to AKI during the duration were studied with male preponderance of 8 (72.7%) and majority (81.8%) belonging to lower social class (IV and V). Their ages ranged between 5 months and 12 years with a mean age of 4.8±3 years. Acute glomerulonephritis (AGN) (n = 5), severe acute diarrhoeal disease (n = 4) and obstructive nephropathy (n =2) were causes of AKI. Peritoneal dialysis was performed manually using percutaneous commercial PD catheters (n=10) and adapted catheter (n=1). Duration of PD ranged from 3 to 17 days (mean: 8.1±4.1 days). The main complications were peri-catheter leakage (n = 6), and catheter obstruction (n = 3), exit wound (n=2) and acute bacterial peritonitis (n = 1). Of the 11 patients, 7 (63.6%) were discharged home alive and well, 3 (27.4%) died and 1(9.1%) left against medical advice. Conclusion: With meticulous attention to aseptic procedure and use of improvised dialysis fluids and catheters or semi-rigid PD catheters where available, PD is an affordable choice of RRT in management of paediatric AKI. Complications are bound to occur and are better anticipated and planned for.

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In most developing countries, data on the pattern of Paediatric Endocrine Disorders is lacking. To describe the pattern of Paediatric Endocrine Disorders as seen in Usmanu Danfodiyo University teaching Hospital (UDUTH), Sokoto, Nigeria, from January 2013 to December 2016. The case files of children seen at the paediatric endocrine/metabolic clinic and those admitted into the wards at UDUTH, Sokoto, from January 2013 to December 2016 were audited retrospectively. Information obtained included age at presentation, gender, principal complaints, final diagnosis and outcome. A total of 37 children presented with various endocrine disorders during the 4 - year- period under review. There were 20(54.1%) males, 15(40.5%) females, and 2(5.4%) patients with genital ambiguity. Patient's age ranged from 3weeks to 15years with a mean age and standard deviation (SD) of 6.9(5.2) years. Majority, 17(46%) of the patients were Adolescents. The endocrine disorders were thyroid disorders- 12(32.4%), diabetes Mellitus 9(24.3%), disorders of energy balance 4(10.8%), disorders of calcium and bone metabolism 4 (10.8%) and pubertal disorders 3(8.1%). Five (13.5%) patients were admitted, four were diabetics, three of which were discharged and 1(2.7%) died. Fifteen (40.5%) patients were lost to follow up in the endocrine clinic. Thyroid disorders, Diabetes Mellitus, Disorders of energy balance, Calcium and bone metabolism and pubertal disorders were the five leading groups of childhood endocrine disorders encountered in our clinical practice in UDUTH, Sokoto.