Venlafaxine is the first antidepressant that acts via inhibiting serotonin and noradrenaline reuptake. Hypertension is observed in doses exceeding 300 mg/day and is the most feared complication. We report a patient with accelerated hypertension after venlafaxine use observed at a dose of 150 mg/day. A 23-year-old patient with symptoms of insomnia, depression, anhedonia, fatigue admitted our clinic. Venlafaxine at a dose of 75 mg/day was initiated after he was diagnosed with major depressive disorder. After 5 months, venlafaxine dose was uptitrated to 150 mg/day due to inadequate response to drug. After using venlafaxine for ten months at the dose of 150 mg/day, he admitted our clinic with headache and epistaxis. He was hospitalized after his blood pressure was measured as 210/170 mmHg. No secondary causes for hypertension were found, and venlafaxine treatment was considered possible etiologic factor. After stopping venlafaxine treatment, his blood pressure was reverted back to normal limits. While mild elevation of blood pressure could be observed after venlafaxine treatment, this case shows that accelerated hypertension with a diastolic blood pressure rise above 120 mmHg could be observed at relatively low doses of venlafaxine. Close monitoring of blood pressure is necessary after initiation of treatment, as accelerated hypertension could cause endorgan damage with potentially catastrophic results.

Introduction: The aim was to investigate the relation between sociodemographic features, anxiety, depression, sleep quality, childhood trauma experiences, and quality of life and bruxism determining the risk factors in people with bruxism. Methods: A total of 200 people were included in the study. Of the patients, 100 were diagnosed with bruxism and 100 were included in the control group. Sociodemographic Data Form, Hospital Anxiety Depression Scale (HAD), The Pittsburgh Sleep Quality Index (PSQI), Childhood Trauma Scale (CTS), Short Form-36 Quality of Life Scale (SF-36) were used. Results: While there was no significant difference between the case group and the control group in terms of age, gender, marital status, and working status, there was a significant difference between educational levels. When the groups were compared a significant difference was found with regard to HAD-A (p<0.05), HAD-D (p<0.01), PSQI (p<0.01) and CTS (p<0.05) scores. While a significant difference was found when KF-36 subscales were examined, with regard to Physical Function (p<0.01), Pain (p<0.05), Social Function (p<0.05) and Mental Health (p<0.01) scores, no significant difference was detected between the subscales of Role Strength (p>0.05), General Health (p>0.05), Vital Energy (p>0.05) and Emotional Role (p>0.05). Regression analysis shows, (PSQI), HAD-D CTS scores predicted bruxism. Conclusion: Higher depression scale scores, bad sleep quality, traumatic childhood experiences increase the risk for bruxism. Paying attention to the mental state of people diagnosed with bruxism in the treatment process and incorporating the psychiatrists in this process may increase the success rate of the treatment.

OBJECTIVE: This study was conducted with an aim to determine whether biochemical parameters could be used to identify the individuals at risk of suicide. METHODS: The experimental group consisted of a total of 46 patients that presented to the emergency department after a suicide attempt. 45 healthy individuals constituted the control group. All subjects were evaluated by using the Beck Depression Inventory (BDI), the Beck Anxiety Inventory (BAI), and the Beck Scale for Suicidal Ideation (BSSI). All subjects were evaluated for leukocyte count, mean platelet volume (MPV), C-reactive protein (CRP), cholesterol, triglyceride levels and neutrophil-lymphocyte ratio (NLR). The Vitamin D levels of the subjects in the experimental group were also measured. RESULTS: The BAI (p < 0.01), BDI (p < 0.01), and BSSI (p < 0.01) scores of the two groups were signifi cantly different. The two groups were also signifi cantly different in terms of CRP (p < 0.01), cholesterol (p < 0.05), NLR (p < 0.01), MPV (p < 0.01), triglyceride (p < 0.01) and leukocyte (p < 0.01) results. The vitamin D levels of the experimental group were found to be below normal vitamin D levels. High CRP levels were found to be a predictor of anxiety symptoms, and MPV and triglyceride levels were found to be predictors of depressive symptoms. CONCLUSION: We believe that biochemical parameters can be used to identify people with increased suicide risk, and suicide rates can be reduced by ensuring that these patients receive mental health care in the early period (Tab. 5, Ref. 42).

ÖzAmaç: Sigara bağımlılığı tüm dünyada ve ülkemizde en önemli halk sağlığı sorunlarındandır. Sigara kullanımına bağlı ortaya çıkan sağlık sorunları nedeniyle her saniyede bir kişi hayatını kaybetmektedir. Sigara bağımlılarında anksiyete, depresyon, çocukluk çağı travmaları ve dürtüsellik çalışılmış olmakla birlikte D Tipi kişilik örüntüsü araştırılmamıştır. Literatürdeki bu eksikliği gidermek için bu çalışma planlanmıştır. Materyal ve Metot: Çalışmamıza sigara bağımlısı olan 151 kişi ve 100 kontrol olmak üzere toplam 251 kişi alınmıştır.

How to cite / Atıf için: Taşdelen Y, Yağcı İ. Anxiety, depression, Type D personality, somatosensory amplification levels and childhood traumas in patients with panic disorders. This is an open access article distributed under the terms of the CreativeCommons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND 4.0) where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. AbstractAim: Persons with type D personality have been shown to be predisposed to depression and anxiety disorders. However, to our knowledge, there are no studies which have investigated the relationship between panic disorder (PD) and type D personality. Our aim in the current study was to determine whether PD was associated with Type D personality, anxiety, depression, childhood trauma and somatosensory amplification by comparing the characteristics of patients with and without PD. Methods: We designed a questionnaire based case-control study. The study group included 100 patients with panic disorder, and control group consisted of 100 healthy individuals. Sociodemographic Data Form, Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Type D Personality Scale (DS14), Childhood Trauma Questionnaire (CTQ) and Somatosensory Amplification Scale (SSAS) were carried out for each participant. Results: The patient and control groups were found to be similar in terms of sex, marriage status, education status and employment status. Compared to the control group, scores for BAI (P<0.01), BDI (P<0.01), CTQ (P<0.01), DS-14 (P<0.01) were found to be significantly higher in the patient group. The frequency of Type D personality was also higher in the patient group. Conclusion: Our findings show that patients with PD have significantly higher scores in anxiety, depression, Type D Personality, CTQ total scores measures compared to controls. We did not find any associations between PD and somatosensory amplification. We believe our findings will contribute significantly to the limited literature on this topic.