Latar Belakang: Survey awal yang dilakukan di SDN 79/VII Desa Kasiro Kecamatan Batang Asai Kabupaten Sarolangun Jambi bahwa prevalensi karies tinggi 78% angka kejadian karies rata – rata anak mengalami karies 4 – 5 gigi dan belum adanya gigi yang dilakukan penambalan. Tingginya angka kejadian karies di Sekolah Dasar 79/VII Kasiro dipengaruhi juga oleh tingkat ekonomi, pengetahuan masyarakat.Metode: Penyuluhan, dilakukan setelah pretest dengan materi pemeliharaan Kesehatan gigi dan cara menyikat gigi yang baik dan benar dengan menggunakan media poster dan phantom gigi. Simulasi, dilakukan setelah anak mendapatkan materi penyuluhan kemudian disimulasikan didepan teman. temannya sehingga dapat dipahami dan di prakttekkan. Demontras, dilakukan saat menyikat gigi bersama dipandu oleh pembimbing dengan menggunakan model phantom gigi. Diskusi, dilakukan setelah penyuluhan dan sikat gigi bagi yang belum memahami dan belum bersih ,menyikat gigiHasil: terjadi Peningkatan Pengetahuan pemeliharaan kesehatan gigi dan mulut menjadi 100%, peningkatan keterampilan dengan menurunnya plak score dari rata-rata 11 gigi menjadi 2 gigi yang masih ada noda disclosingKesimpulan: Terjadi Peningkatan Pengetahuan dan keterampilan tentang cara menyikat gigi yang baik. ABSTRACTBackground: An initial survey conducted at SDN 79/VII in Kasiro Village, Batang Asai District, Sarolangun Regency, Jambi, found that the prevalence of caries was high, 78%, the average caries incidence rate was 4-5 teeth for children and there were no teeth filled with fillings. The high incidence of caries in Kasiro 79/VII Elementary School is also influenced by the economic level and knowledge of the communityMethods: Counseling, carried out after the pretest with dental health maintenance material and how to brush teeth properly and correctly using posters and dental phantom media. Simulation, carried out after the child gets the counseling material is then simulated in front of friends. friends so that they can be understood and practiced. Demontras, carried out while brushing teeth together guided by a supervisor using a dental phantom model. Discussion, carried out after counseling and tooth brushing for those who do not understand and are not yet clean, brush their teethResult: there was an increase in knowledge of maintaining oral health to 100%, an increase in skills with a decrease in plaque score from an average of 11 teeth to 2 teeth with disclosing stainsConclusion: There is an increase in knowledge and skills about how to brush your teeth properly.

The tuberculosis treatment control program is constrained by the outbreak of TB that is resistant to anti-tuberculosis drugs (OAT), especially multidrug-resistant tuberculosis. Confirmation of tuberculosis drug resistance really needs to be done in each area considering that there are variations in phenotypes and genotypes in each region through laboratory tests such as molecular biology tests. Aim of study to determine the prevalence of Mycobacteriumtuberculosis resistance to pyrazinamide antibiotics by PCR technique. This research is a descriptive exploratory study which has been carried out in the molecular biology laboratory of West Nusa Tenggara Provincial Public Hospital. The sample in this study was positive TB sputum obtained from Patut Patuh Patju Hospital The Province of West Nusa Tenggara. The results showed that 5 of the samples were pyrazinamide resistant. Concluded that Resistance to pyrazinamide antibiotics was found from 10 samples, 5 of which had developed resistance to pyrazinamide antibiotics.

Diabetes mellitus is a disease that occurs due to increased blood glucose levels (hyperglycemia) due to disorders of the pancreas. Mangrove leaves are known as herbal plants that can reduce blood glucose levels because it contains flavonoid compounds that can repair damaged pancreatic β cells and stimulate pancreatic β cells to produce the hormone insulin. This study aimed to determine the effect of Rhizophora leaf extract administration in reducing blood glucose levels of mice. This research was an experimental laboratory with the approach the post-test only control group design. This test used 5 groups, consisting of negative control group, positive control group (Glibenclamide 5 mg/kg BW), KP1 (extract 250 mg/kg BW), KP2 (extract 500 mg/kg BW), KP3 (extract 700 mg/kg BW). Measurement of fasting blood glucose levels using glucometer. The results showed that the administration of Rhizophora leaf extract in the KP1, KP2, and KP3 treatment groups was able to reduce blood glucose levels compared to before being treated, although the decrease was not yet up to normal limits. The conclusion was that the Rhizophora leaf extract was able to reduce fasting blood glucose levels with the highest percentage reduction in KP2 at a dose of 500 mg/kg BW by 29%.

Antibiotics are empirically used as drugs to treat bacterial infections, but the irrational use of antibiotics causes bacterial resistance to certain antibiotic regimens, therefore solutions are needed to explore alternative drugs. This study aims to explore medicinal plants that are able to inhibit Pseudomonas aeruginosa bacteria that are resistant to quinolones and cephalosporins. The method used is descriptive observational and antibacterial activity test of plant extracts using the well diffusion method. Three plant extracts were used, binahong extract (Andredera cordifolia), tomato fruit extract (Lycopersicon esculentum), and aloe vera extract (Aloe vera). The results showed that only tomato extract inhibited Pseudomonas aeruginosa bacteria with a strong category, while binahong and aloe vera extracts could not inhibit the test bacteria. It was concluded that tomato fruit extract might be an alternative as a medicinal plant because it was able to inhibit P. aeruginosa resistant to quinolones and cephalosporin antibiotics.

Diabetes mellitus can cause both acute and chronic complications, one of which is diabetic nephropathy. Therefore, it is necessary to look for problem solving with healthy living behaviors. The purpose of implementing healthy lifestyle behavior of people with diabetes mellitus is to slow the occurrence of complications. Healthy life behaviors that are implemented by people with diabetes mellitus are knowledge, dietary rules, physical exercise, drug therapy, to monitoring glucose levels. The purpose of this study was to determine the relationship between healthy living behavior with HbA1c values and increased creatinine levels in people with diabetes mellitus. The research method used was observational with cross sectional approach. The number of samples used was 54 people with diabetes mellitus. This research was conducted by distributing questionnaires and examining HbA1c levels and creatinine levels by using a statistical spearmen test to determine the relationship. Statistical test results show the relationship between healthy behavior with HbA1c is 0, 224 > 0.05 which means there is no relationship between healthy living behavior with HbA1c value and there is no direct relationship between HbA1c value with increased creatinine levels. While the value of the relationship between healthy behavior with an increase in creatinine levels is 0.021 < 0.05 and has a strength of 313 and the direction of a negative relationship, which means there is a negative relationship between healthy behavior with an increase in creatinine levels in patients with diabetes mellitus. This indicates that the better the healthy living behavior, the lower creatinine levels in diabetics even though there is no direct relationship with HbA1c values with creatinine levels, so that healthy living behavior can be one way to prevent complications of diabetes mellitus.