after approval by the Committee on Animal Research and Ethics. Thirty healthy male SPF Sprague-Dawley rats were randomly divided into the control group, the model group, and the dexamethasone group by random number table, with 10 rats in each group. On the 1st and 8th day, 1 mL of ovalbumin (OVA) (1 mg) + Al (OH) 3 (100 mg) saline solution was intraperitoneally injected for sensitisation, and the rats were placed in a semi-closed container.

Hypothalamic pituitary gonadal axis is affected by acute stress which results in transient suppression of gonadotropin secretion. In stressful conditions, there