Cisplatin is one of the most potential and widely used drugs for the treatment of various solid cancers such as testicular, ovarian, head and neck, bladder, lung, cervical cancer, melanoma, lymphomas, and several others. 1 Multiple cutaneous adverse effects have been reported with this molecule, such as skin rashes or nail changes.To date, we have not found a documented case of psoriasiform eruption due to cisplatin. Here, we report the observation of a psoriasiform eruption in an adult patient who received a cure of cisplatin.A 76-year-old patient, with a history of chronic heavy smoking, was treated for small cell lung cancer with cisplatin ( 40mg/m 2 ) and etoposide-based chemotherapy without growth factors nor concomitant radiotherapy. Four days after the first cure, he develops a pruritic rash. Clinical examination revealed erythematous plaques with hyperkeratotic scales on the trunk, back, four extremities, and periorbital area. (Figure 1A, B).No nail changes were noted.
Syringocystadenoma papilliferum is a uncommon benign cutaneous tumor seen to arise from the pluripotent cells with the potential to exhibit either apocrine or eccrine lineage. We report the dermoscopic features of a case of de novo syringocystadenoma papilliferum. Clinically the lesion was characterised by a nodular and crusted surface. Dermoscopically, yellowish-white structures were the prevalent feature.
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