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Fibroadenomas are benign tumours of the breast. They are usually single, firm, rubbery masses, slow-growing and well encapsulated. Giant fibroadenomas are fibroadenomas at least 5cm in size or at least 500g in weight. The peculiarities of the index case include the massive size and weight of the breast, causing asymmetry and tissue distortion with little or no normal breast tissue on ultrasound scan. Also, such massive weight has not been reported in the literature as suggested by extensive search on databases such as Pubmed and Google Scholar. The main concern of the patient was the rapid growth over a year, with the attendant risk of malignancy. The mass was firm, lobulated, with a solitary axillary lymph node. An initial clinical diagnosis of phyllodes tumour was made. However, pre-operative Tru-cut biopsy histology suggested fibroadenoma and was confirmed using the excised post-operative specimen. Simple mastectomy with axillary lymph node excision was carried out. In conclusion, a large breast tumour may not be malignant. However, mastectomy may be a treatment option despite the benign nature of the tumour.

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Background: Cancer is increasingly becoming a major cause of morbidity and mortality, aggravated among women in developing countries because of increasing longevity, population growth and lack of capacity for treatment. Aim: To highlight the cancer burden among Nigerian females and emphasize the need for a grassroots approach towards prevention and early detection. Study design: This was a descriptive cross-sectional study. Methodology: The study was retrospective, analysing data from histopathology reports of cases of cancer in females as diagnosed over 20 years (2000-2019) in the Department of Anatomical Pathology, University of Benin Teaching Hospital, Benin City, Nigeria. Results: Over 56% of all cancers affected females with 64.9% of cases in the 4th-6th decades. Cancers of the breast, uterine cervix, colon and rectum, uterine corpus, ovary, haematopoietic and lymphoreticular system, and thyroid contributed 36.8%, 20.5%, 4.9%, 3.3%, 2.7%, 2.2% and 2.2% of cancers respectively. Conclusion: Cancer among Nigerian females is increasing in incidence in the face of the existing weak treatment framework. There is urgent need to invest in cancer prevention and early detection strategies using grassroots-oriented and pre-existing structures to achieve a  reversal of this ugly trend.