Water resources in the Southern African Development Community (SADC) play an intrinsic role in regional development. As a result, water is a highly sensitive issue, complex to understand and demanding to govern, in terms of effective and equitable use and distribution. Growing awareness of the complex challenges facing water and the cross-cutting impacts that these challenges have on the region has led to the recognition that these challenges demand more integrated levels of ingenuity and expertise from a diverse set of actors working in a transdisciplinary manner.In response to these realisations a significant body of work has emerged that attempts to determine the criteria of a transdisciplinary approach and how it can be operationalised. This has led to significant progress in gaining an understanding of 'transdisciplinary team' approaches. These transdisciplinary teams have tended to work at the localised or project level of problem response. However, despite this progress, little work has been done on how to upscale transdisciplinary research and practice to the regional level. This is a significant gap given the fact that the source of many complex problems lies at the regional level even if the effects of these problems are localised. Also, little has been done to try to move the transdisciplinary discourse beyond the transdisciplinary team in order to understand how to groom and develop 'transdisciplinary individuals' who have the competence and talent to rise to the complex challenge of fostering regional economic development, of which water is a key component.Given this context, this paper builds on the existing literature in transdisciplinarity and its different conceptualisations in relation to water in Southern Africa. Firstly, it interrogates the cross-cutting role of water in regional socio-economic development in the SADC region. Secondly, it examines the need for transdisciplinary responses to regional socio-economic development. Thirdly, this paper strives to make a valuable contribution to knowledge in that it attempts to take the transdisciplinary discourse beyond 'the team' model to examine the role of the individual and the internalisation of transdisciplinarity as a mindset beyond collective models. In this regard, the paper emphasises the need for 'transdisciplinary individuals' to rise to the complex challenge of regional integration, and particularly, the role of the younger professionals in this process.

In this paper the authors seek to identify the most appropriate model for a regional co-ordination mechanism for cholera preparedness, response and prevention. The qualitative mixed-method data collection approach that was followed revealed the need for alternative solutions, including a socio-political understanding of cholera responses at different levels of scale and at different stages of an outbreak. Important areas that need to be understood include the multiplicity of actors and the complexity of their interaction, the importance of building local capacity, the need for varying responses at different levels of scale, the need for improved inter-and intra-country co-ordination and information exchange, the importance of cultural belief systems and the impact of the media on the response to cholera outbreaks. Ultimately, despite the proposed co-ordinating role that the Southern African Development Community (SADC) can play in a regional cholera response effort, the onus remains on states to build capacity at the local level and to capacitate local communities to drive response efforts semi-autonomously.