Objective: This study was undertaken to justify and validate a very frequent traditional use of a very well-known and widely used plant by a large part of the Moroccan population. It's about Corrigiola telephiifolia, and the activity in question is the diuretic activity. Methods: The aqueous ethanol root extract of corrigiola telephiifolia (200 mg/kg, 400 mg/kg, and 700 mg/kg) was orally administered to rats. The urinary excretion rate and pH, and electrolyte excretion were measured in the urine of saline-loaded rats. Negative control group received only an equivalent volume of distilled water, while the positive control groups received the diuretic drugs hydrochlorothiazide at dose 10 mg/kg. Results: The results showed that hydrochlorothiazide induced significant diuresis and electrolytes excretion at 1, 6 and 24 h after the treatment. Both the higher doses of the extract produced a significant increase in urine volume than the control from the first hour until the end of observation. However, the lowest dose increased significantly only at 24 h after the treatment. With regard to the electrolyte excretion, the tested doses of CTRE which have shown a significant increase in Na + , K + and Clexcretion in comparison to normal control rats, are 400 and 700 mg/kg bw. Conclusion: These findings collectively indicate that the extracts of C. telephiifolia have a potential to induce diuresis markedly, and providing evidence, for its traditional use.

According to the World Health Organization, 80% of the population in developing countries is engaged in traditional medicine. Consequently, the issue of poisoning by plants is not negligible. The objective of this study is to evaluatethe therapeutic and toxicological knowledge of herbalists of the most reported plants in the anti-poison center of Morocco. Field study by direct interview with 20 herbalists of the Rabat-Témara region to assess their therapeutic and toxicological knowledge of the most reported plants in the anti-poison center of Morocco, as well as the conditions of their sale, through a questionnaire. A total of 20 herbalists were accepted to participate in the study. Not all of them had a herbalist certificate and only two knew all the plants studied. The most recommended plant by herbalists to their clientele was Atractylis gummifera. Although the law prohibits the possession and sale of any toxic plant, the availability of these plants to the herbalists surveyed varies between 100% for A. gummifera and 0% for Hyoscyamus falezlez. None of the herbalists received notifications of cases of intoxication. Although the therapeutic knowledge of herbalists was well advanced, their toxicological knowledge was not, so we note that the majority of herbalists did not know with precision the possible side effects of the plants sold, or how they could be used safely. Although plants have real and beneficial effects, they are not devoid of side effects that can sometimes be fatal; hence the need to focus on regulation of the functions of the herbalist.

The study concerns the fruit of the argan tree (Argania spinosa L. Skeels) from Jbel Takermine (Figure 2); a mountain of the western chain of Beni-Snassen (north-east of Morocco) that culminates at 317 m. The Beni-Snassen lands are characterized by a variable lithology; the geological formations are formed, from the bottom to top, by limestone, marsh

Introduction. La douleur est un motif de consultation très fréquent, chaque syndrome algique justifie des modalités particulières de prise en charge thérapeutique, selon son origine, ses caractéristiques et le terrain. L’objectif de l’étude est d’évaluer la prise en charge de la douleur à l’hôpital afin de déceler d’éventuelles déficiences. Matériel et méthodes. Un questionnaire a été destiné aux médecins de tous les services de l’hôpital. Les principaux thèmes étaient : le statut du médecin prescripteur, les méthodes et le temps consacré pour l’évaluation de la douleur, les antalgiques prescrits ainsi que les voies d’administration, la douleur chez l’enfant et enfin l’objectif de la prise en charge de la douleur. Résultats. On a reçu 100 réponses, avec 22% généralistes, 40% résidents et 17% des professeurs, dont 37% ont reçu une formation sur la douleur. 62% ont un protocole de prise en charge de la douleur dans leurs services. 81% prescrivent un antalgique dès l’expression de la douleur par les patients. La moyenne du temps, pour évaluer la douleur a été de 5,82 minutes avec un écart type de 4,92. 52% utilisent la méthode EVA, 4% l’EN, 66% évaluent la douleur selon les plaintes des patients, 35% selon les réactions des patients, 23% selon les mouvements des patients, 20% selon l’expression faciale des patients. 98% prescrivent le paracétamol en première intention, 45% de la morphine, 72% des AINS, 30% du tramadol et 24% utilisent en plus de ces analgésiques, d’autres molécules tel que le néfopam, la codéine. Les obstacles rencontrés lors de la prise en charge de la douleur sont 27% d’ordre économique, 24% dû à la non adhésion des patients, 36% la non disponibilité de certains antalgiques. 89% estiment que le niveau de prise en charge de la douleur dans le service est excellent, contre 56% avec un niveau moyen et 8% un niveau insuffisant. 83% affirment que la prise en charge de la douleur est obligatoire et 82% faisant partie d’une assurance qualité des soins. Conclusion. La prise en charge de la douleur est pluridisciplinaire, les professionnels de santé doivent avoir une formation sur la nécessité de prise en charge de la douleur qui entre dans le cadre de l’assurance qualité des soins et devient obligatoire pour la prise en charge du patient.