Identifying causes of wildlife mortality can yield an understanding of the factors that impact wildlife health. This is particularly significant for species that are facing population declines because this information can inform conservation and management practices. We evaluated causes of mortality for bats in British Columbia submitted to the provincial veterinary laboratory between 2015 and 2020, and assessed whether cause of death varied by species and/or was associated with bat characteristics (e.g., sex and body condition). Of the 275 bats included in this study, the most frequent cause of death was cat depredation (24%), followed by blunt force trauma (23%). Bats that died by cat depredation tended to be in good body condition as compared to those that died from other causes, and male bats were more likely to die from blunt force trauma compared with females. Emaciation was also an important cause of mortality (21%) and 8% of bats died due to rabies, with the greatest rabies prevalence in Eptesicus fuscus (Palisot de Beauvois, 1796). Our results demonstrate the potential burden of cat depredation on healthy bats and highlight the need for strategies to decrease cat depredation to support healthy bat populations.