Objective: To determine the frequency of dyslipidemia in Helicobacter pyloriinfected patients. Patients and methods: This cross sectional descriptive study of six monthsstudy was conducted at Liaquat University Hospital Hyderabad from 01-03-2012 to 31-08-2012. All the patients between 19 to 60 years of age present with symptoms of dyspepsia,bloating or epigastric discomfort for more than 01 week duration were admitted and evaluatedfor Helicobacter pylori infection. Thereafter the positive cases (Helicobacter pylori infectedpatients) were further evaluated for dyslipidemia. Results: During six month study period,total 144 patients (95 males and 49 females) with Helicobacter pylori infection were evaluatedfor dyslipidemia (lipid profile). Majority of patients were from urban areas 110/144 (76%).The mean ±SD for age of patients with Helicobacter pylori infection was 35.94±10.77. Themean age ±SD of dyslipidemic patient was 32.62±6.52. The dyslipidemia was identified in 87(60.4%) patients, of which 51(58.6%) were males and 36(41.4%) were females. Regarding thepattern of dyslipidemia, ten (11.4%) patients had raised serum triglycerides level, twenty eight(32%) had raised LDL-C level, twenty six (28.9%) had raised serum cholesterol level, seven(8.7%) had low HDL-C level and sixteen (18.3%) had mixed dyslipidemia. The mean ±SD ofhypertriglyceridemia, ↑HDL-C, ↑LDL-C and hypercholesterolemia in dyslipidemic Helicobacterpylori infected was 280.72±22.85, 24.21±2.63, 180.63±12.98 and 285.21±23.63 respectively.Conclusions: The H. pylori infected patients are prone to acquire dyslipidemia, therefore thepresent study observed 60.4% prevalence of dyslipidemia with male predominance (58.6%)
Pharmacy is an expanding profession with new and expanded duties for pharmacists. Pharmacology training should adjust to local and global trends to graduate quality pharmacists1. The five years of basic pharmacy education is inadequate for excellent quality of treatment, which might impair patients' health. Several nations, including the USA, have expanded basic pharmacology training to 6 years and established Pharm D as entrance level for any area of practice2. Countries that have implemented postgraduate training produce practice-ready pharmacists in varied sectors, depending on specialty and local requirements. Regional pharmacy authorities supply a large number of institutional rotation locations for pharmacy students, whereas hospital rotations have become a career necessity3. This rotation aims to provide students experience as pharmacists in a multidisciplinary context. The rotation's goals and activities include comprehending patients' drug-related requirements, pharmacists' regulatory, ethical, and professional duties, and medication distribution4. This clinical rotation offered a number of issues for institutions, especially in offering possibilities for students to engage in the pharmacist's job. Students should perform a set of specific clinical activities for which they are educated in hands-on workshops, followed by observation by a clinician or physician. Students do activities under indirect supervision after skill assessment. This technique lets students participate in direct medical care and help specific patients.5The duration of the rotation is inadequate for skill development, thus students must do duties under indirectly supervision of the institution's physician to begin hospital pharmacy practice.
Objective: To determine the frequency of modifiable and non-modifiable risk factors of acute ST elevation myocardial infarction at tertiary care Hospital. Methods: This study was conducted in the department of Cardiology, Liaquat University Hospital Jamshoro, from July 2019 to January 2020. All the patients those presented with myocardial infarction and either of gender were included in the study. After taking complete clinical examination and diagnosis, patients were interviewed regarding family history, hypertension, diabetes, smoking, alcohol consumption, dietary habits and life style activities. Non modifiable predisposing risk factors were defined as age, gender and family history. Modifiable risk factors were defined as elevated serum cholesterol, presence of type II DM, cigarette smoking, obesity, a sedentary lifestyle and hypertension. All the data was recorded in self-made proforma. Data analysis was done by SPSS version 21 Results: Total 100 patients were studied; most common age group was 41-50 years (45.0%), and 51-60 years (35.0%). According to the types of myocardial infarction, Acute anterior wall MI was in 25.0%, Acute inferior MI was in 20.0%, EXT ANT WALL MI was in 16.0% and Acute inferior +RV MI was in 15.0% of patients. Elevated age in 70.0% and male gender in 69% of cases were found to be most common non-modifiable risk factors, while frequently seen Modifiable risk factors were smoking, type II diabetes, hypercholesteremia, hypertension, and physical activities. Conclusion: It was observed that elevated age, male gender, smoking, diabetes and hypertension are frequent risk factors for ST elevation myocardial infarction. Keywords: Modifiable, non-modifiable, risk factors, MI
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