Background. Neurogenic myositis ossificans is a rare entity defined by the development of soft tissue ossifications in patients with paraplegia or tetraplegia following neurological pathologies, often after cranial or spinal cord trauma. The diagnosis is based on imaging, in particular CT scan, which often reveals the presence of intramuscular ossifications of periarticular location. Treatment is based on analgesics, physiotherapy, and surgery as a last resort. Case Report. We present a case of neurogenic myositis ossificans in a 26-year-old patient followed for axonal polyneuropathy secondary to vitamin deficiency. Conclusions. Neurogenic myositis ossificans is a rare entity but is easily diagnosed, given the context of severe neurological disorders and the characteristic appearance on CT scan. In doubtful and atypical cases, a biopsy with histological study is recommended.