The proposed algorithm is able to effectively deal with both the presence of motion and the geometric distortions, increasing accuracy and reproducibility in diffusion parameters estimation.

No abstract

By operating directly in the k-space, the proposed method is able to provide an exact characterization of noise for any Cartesian pattern sub-sampled along the two phase-encoding directions. Exploitation of the symmetries and separability into independent blocks through the image reconstruction procedure allows us to overcome the computational challenges related to the very large size of the covariance matrices involved.