Objectives: To compare the effect of low-volume high-intensity interval training (HIIT) with moderate-intensity continuous training (MICT) on fat mass, cardiometabolic profile, and physical capacity, and confirm its feasibility in older women. Methods: Inactive older women (60–75 years) were randomly assigned to 8 weeks of either HIIT (75 min/week; n = 9) or MICT (150 min/week; n = 9). Body composition, fasting metabolic profile, cardiovascular risk (Framingham score), and physical capacity (senior fitness test, peak oxygen uptake) were assessed before and after the intervention. Feasibility was evaluated with completion rate (training compliance; dropout rate) and affective response (Feeling Scale; pre- and postexercise). Results: Total cholesterol level, non-high-density lipoprotein cholesterol level, and the Framingham risk score decreased in both groups (ps ≤ .03). Although peak oxygen uptake remained unchanged, the 6-min walk test distance increased (p < .0001), irrespective of the group. Completion rate and affective responses were not different between groups (ps ≥ .38). Conclusion: A short-term HIIT program is feasible and provides as much benefits as MICT in older women.
Aims/hypothesis For individuals living with type 1 diabetes, closed-loop insulin delivery improves glycaemic control. Nonetheless, maintenance of glycaemic control during exercise while a prandial insulin bolus remains active is a challenge even to closed-loop systems. We investigated the effect of exercise announcement on the efficacy of a closed-loop system, to reduce hypoglycaemia during postprandial exercise. Methods A single-blind randomised, crossover open-label trial was carried out to compare three strategies applied to a closed-loop system at mealtime in preparation for exercise taken 90 min after eating at a research testing centre: (1) announced exercise to the closed-loop system (increases target glucose levels) in addition to a 33% reduction in meal bolus (A-RB); (2) announced exercise to the closed-loop system and a full meal bolus (A-FB); (3) unannounced exercise and a full meal bolus (U-FB). Participants performed 60 min of exercise at 60%VO 2peak 90 min after eating breakfast. The investigators were not blinded to the interventions. However, the participants were blinded to the sensor glucose readings and to the insulin infusion rates throughout the intervention visits. Results The trial was completed by 37 adults with type 1 diabetes, all using insulin pumps: mean±SD, 40.0 ± 15.0 years of age, HbA 1c 57.1 ± 10.8 mmol/mol (7.3 ± 1.0%). Reported results were based on plasma glucose values. During exercise and the following 1 h recovery period, time spent in hypoglycaemia (<3.9 mmol/l; primary outcome) was reduced with A-RB (mean ± SD; 2.0 ± 6.2%) and A-FB (7.0 ± 12.6%) vs U-FB (13.0 ± 19.0%; p < 0.0001 and p = 0.005, respectively). During exercise, A-RB had the least drop in plasma glucose levels: A-RB −0.3 ± 2.8 mmol/l, A-FB −2.6 ± 2.9 mmol/l vs U-FB −2.4 ± 2.7 mmol/l (p < 0.0001 and p = 0.5, respectively). Comparison of A-RB vs U-FB revealed a decrease in the time spent in target (3.9-10 mmol/l) by 12.7% (p = 0.05) and an increase in the time spent in hyperglycaemia (>10 mmol/l) by 21% (p = 0.001). No side effects were reported during the applied strategies.Sémah Tagougui and Nadine Taleb contributed equally to this work.
that included demographics, chronic conditions, rural location, prior hospitalizations, and high vs. low hurricane impact revealed that post-hurricane change in personal care services was associated with hospital admissions in the three months after the hurricane. Compared to no change in personal care services, decrease in personal care services was associated with increased incidence of hospital admissions (IR = 0.549; 95%CI=0.435,0.663;p<0.001), whereas increase in personal care services was associated with decreased incidence of hospitalization (IR=-0.61; 95%CI=-0.714,-0.508;p<0.001). Disaster-related reduction in PCS increases vulnerable older adults' risk for hospital admissions. Methods Participants included 20 patients with MCI and their respective care partners who were actively deciding whether to pursue AI. All participants underwent pre-testing counseling (PTC) including: overviews of MCI, AD, and AI, potential pros/cons of AI, and implications for AD risk. Following PTC, participants were encouraged to carefully consider whether to pursue AI. Within 2 weeks of PTC, qualitative interviews were conducted using a semi-structured interview guide with openended questions about the decision making process, including which factors were considered during the decision. Interview transcripts were coded and categorized using content analysis. HOW DO PATIENTS WITH MILD COGNITIVEResults Patients and care partners consistently reported the potential to gain more information about the underlying cause, or likely course, of their MCI as a major motivator for pursuing AI. Many were actively anticipating their emotional and behavioral reactions to AI results. Upon probing, most acknowledged the limitations and potential drawbacks of AI (e.g., "They aren't going to find something on the scan and give me a pill and I'll be better."). Yet, there were 11 instances of misunderstanding or overstating the potential value of AI (e.g., "It will tell me how far along I am.").Conclusion Even with PTC, some individuals may disproportionately emphasize potential benefits when considering AI. The impact of high-intensity interval training (HIIT) compared to the current exercise recommendations (moderate intensity continuous aerobic exercise; CONT) has to be verified in obese older women before being used by health professionals. Objective: The purpose of this study is to compare the effect of HIIT to CONT on body composition, metabolic profile and affective responses in obese elderly. Methods: A total of 20 older and sedentary women (60-75 years) with abdominal obesity (waist circumference ≥ 88 cm) are currently recruited and randomized to one of the following group: 1) HIIT (n=10); 2) CONT (n=10). All variables are measured before and after 8 weeks of intervention: Anthropometry (weight, height, body mass index), body composition (fat mass [FM], lean body mass [LBM], visceral adipose tissue [VAT]; DXA), metabolic profile (fasting lipid profile, glucose and insulin) and physical capacity (senior fitness test). Affective responses ...
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