This paper presents dynamic response and fatigue analyses of several bottom‐mounted offshore wind turbine (OWT) models, simulated in the aero‐hydro‐servo‐elastic simulation tool FAST. The distinction between the models is the foundations, which are modelled with different methods, concepts, and dimensions. The US National Renewable Energy Laboratory has developed a 5‐MW reference turbine supported on a monopile, the NREL 5MW, which was used as a reference model in this paper. The paper presents the implementation and comparison of two different foundation modeling methods, referred to as the simplified apparent fixity method and the improved apparent fixity method. Furthermore, sensitivity analyses of different monopile dimensions were performed, followed by sensitivity analyses of suction caisson foundations of different dimensions. The final part of the paper presents fatigue analyses for the foundation models considered in this study subjected to 17 load cases. Fatigue damage, fatigue life, and damage equivalent loads were calculated, as well as the relative fatigue contribution from each load case.