ABSTRAKPenelitian ini bertujuan mengetahui pengaruh pemberian kacang panjang (Vigna unguiculata) terhadap kadar glukosa darah mencit (Mus musculus) yang diinduksi aloksan. Dalam penelitian ini digunakan 12 ekor mencit dengan berat 25-40 g yang secara klinis dinyatakan sehat. Mencit dibagi menjadi empat kelompok perlakuan, masing-masing kelompok perlakuan terdiri atas tiga ekor mencit. Kelompok K0 adalah kelompok kontrol negatif, hanya diberi akuades. Kelompok K1, K2, dan K3 adalah kelompok yang diinduksi aloksan masing-masing 0,5 ml. Kelompok K1 adalah kontrol positif. Kelompok K2 diberikan 100 g kacang panjang yang dicampur dengan akuades 50 ml. Kelompok K3 diberikan 100 g kacang panjang yang dicampur dengan 100 ml akuades. Kacang panjang diberikan 0,5 ml secara oral pada pagi dan sore hari selama tujuh hari. Pada hari ke-8 dilakukan pemeriksaan kadar glukosa darah. Rata-rata kadar glukosa darah setelah perlakuan K0; K1; K2; dan K3 masing-masing adalah 142,00±23,39; 167,00±10,54; 122,67±12,50; dan 154,67±16,26 mg/dl (P>0,05). Dapat disimpulkan bahwa pemberian kacang panjang selama tujuh hari tidak menurunkan kadar glukosa darah mencit yang diinduksi aloksan. ____________________________________________________________________________________________________________________ Kata kunci: aloksan, glukosa darah, kacang panjang
ABSTRACT
The aim of this research was to find out the effect of long bean (Vigna unguiculata) on level of blood glucose on mice (Mus musculus
The aim of this research was to find out the effect of long bean (Vigna unguiculata) on level of blood glucose on mice (Mus musculus) induced by alloxan. Twelve mice with the weigh of 25-40 grams and clinically healthy were used in this research. All mice were randomly divided into 4 treatment groups, 3 mice each. K0 was negative control group, only given aquadest. K1, K2, and K3 groups were induced by alloxan 0.5 ml. K1 group was positive control. K2 group was fed with 100 grams long bean mixed with 50 ml distilled water. K3 group was fed with 100 grams long bean mixed with 100 ml distilled water. Long bean was fed orally 0.5 ml every morning and evening for 7 consecutive days. On day eight the examination of blood glucose level was performed. The average level of blood glucose were K0 (142.00±23.39), K1 (167.00±10.54), K2 (122.67±12.50), dan K3 (154.67±16.26) mg/dL. In conclusion, the administration of long bean for seven consecutive days does not decrease blood glucose level on mice induced by alloxan.Key words: blood glucose, alloxan, long bean
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