In this paper we report on the optimization of an experimental arrangement of DBD type, aiming to work in a He + N 2 environment, applied to the surface treatment of polymers. Here the discharge was systematically investigated on an extended range of the gas mixture composition, using electric parameter measurement and emission spectroscopy. The effects of the He + N 2 -DBD treatment on the surface of a test material are examined, compared with results obtained on the He-DBD treatment. The surface characterization was performed using contact angle measurement, AFM imaging and XPS analysis, so allowing the selection of treatment parameters for reproducible, efficient and stable surface modification.
Catechol-O-methyltransferase (COMT) has been implicated in schizophrenia by its function through its roles in monoamine neurotransmitter metabolism and its impact on prefrontal cognition, and also by its position through linkage scans and a strong cytogenetic association. Further support comes from association studies, especially family-based ones examining the COMT variant, Val 108/158 Met. We have studied eight markers spanning COMT and including portions of the two immediately adjacent genes, thioredoxin reductase 2 and armadillo repeat deleted in velocardiofacial syndrome (ARVCF), using association testing in 136 schizophrenia families. We found nominal evidence for association of illness to rs165849 (P ¼ 0.051) in ARVCF, and a stronger signal (global P ¼ 0.0019-0.0036) from three-marker haplotypes spanning the 3 0 portions of COMT and ARVCF, including Val 108/158 Met with Val 108/158 being the overtransmitted allele, consistent with previous studies. We also find Val 108/158 Met to be in linkage disequilibrium with the markers in ARVCF. These findings support previous association signals of schizophrenia to COMT markers, and suggest that ARVCF might contribute to this signal. ARVCF, a member of the catenin family, besides being a positional candidate, is also one due to its function, that is, its potential role in neurodevelopment, which is implicated in schizophrenia pathogenesis by several lines of evidence. Molecular Psychiatry (2005) 10, 353-365.
This study focuses on the level of membership in associations of the migrant population in Spain. Three types of civic engagement are considered: participation in all types of civic associations, in associations for immigrants and in non-immigrant associations. The article investigates whether immigrants coming from countries with higher levels of civic participation are more likely to participate in civic associations and if immigrants who have lived longer in and stayed in closer contact with a home country with a higher level of civic participation are more likely to join civic associations. Data used come from the Spanish National Immigrant Survey (2007) and the World Values Survey (2000, 2005). The results of multilevel logistic regressions show that immigrants who have spent more time in a more participatory context at origin and who are in closer contact with these societies are more likely to get involved in civic associations at destination.
Given the paucity of archaeogenetic data available for medieval European populations in comparison to other historical periods, the genetic landscape of this age appears as a puzzle of dispersed, small, known pieces. In particular, Southeastern Europe has been scarcely investigated to date. In this paper, we report the study of mitochondrial DNA in 10th century AD human samples from Capidava necropolis, located in Dobruja (Southeastern Romania, Southeastern Europe). This geographical region is particularly interesting because of the extensive population flux following diverse migration routes, and the complex interactions between distinct population groups during the medieval period. We successfully amplified and typed the mitochondrial control region of 10 individuals. For five of them, we also reconstructed the complete mitochondrial genomes using hybridization-based DNA capture combined with Next Generation Sequencing. We have portrayed the genetic structure of the Capidava medieval population, represented by 10 individuals displaying 8 haplotypes (U5a1c2a, V1a, R0a2’3, H1, U3a, N9a9, H5e1a1, and H13a1a3). Remarkable for this site is the presence of both Central Asiatic (N9a) and common European mtDNA haplotypes, establishing Capidava as a point of convergence between East and West. The distribution of mtDNA lineages in the necropolis highlighted the existence of two groups of two individuals with close maternal relationships as they share the same haplotypes. We also sketch, using comparative statistical and population genetic analyses, the genetic relationships between the investigated dataset and other medieval and modern Eurasian populations.
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