The aim of this study was to investigate the effect of quantum learning model on science teacher candidates' self-efficacy and communication skills. One group pre-test post-test experimental design was performed in the study. The research was carried out with 20 teacher candidates having education in third grade of Division of Science Education in Ahi Evran University. A total of 16 hours' seminar was given to the teacher candidates in the research group about "Quantum Learning Model" and the techniques used in quantum learning model. The application of the research was performed in 8 weeks and in a total of 32 hours with laboratory experiments arranged in accordance with the "Quantum Learning Model" in the course of Science Teaching Laboratory Practices-II. Before and after the experimental studies, "Science Teaching Self-Efficacy Belief Questionnaire" and "Self-Awareness Inventory" were performed on teacher candidates. The obtained data were analyzed by SPSS package program. According to the results of the research, there was no significant difference between the science teacher candidates' science teaching self-efficacy pre-test and post-test mean scores. Between the mean scores of science teacher candidates in science teaching self-efficacy pre-test and post-test, there was a significant difference in favor of post-test.