Aims and Objective:To find out and compare peri implant strain developed in four different types of implant supported prostheses i.e., cement retained splinted, cement retained non splinted, screw retained splinted, screw retained non splinted.Methodology:Four implant analogues were placed in a polyurethane mandibular model at the position of left and right first and second molar. Abutments were fixed to the implant at a torque of 25Ncm. Two such models were made. Four different prostheses were placed on abutment of each model i.e screw retained splinted, screw retained nonsplinted, cement retained splinted, cement retained non splinted. Four strain gauges were attached on the model, two on the buccal and two on the lingual aspect of each implant. Static load of 400N was applied on the prosthesis using universal testing machine. Load application was done ten times for each model and peri implant strain was measured.Results:The mean peri implant strain (±SD) generated was found to be highest in non-splinted screw retained (1397.70 ± 44.47 microstrains and 1265.90 ± 42.76 microstrains) and least in splinted cement retained (630.70 ± 31.98 microstrains and 519.60 ± 32.48 microstrains) in both 1st and 2nd molars respectively.Conclusions:Splinted crowns produce less peri implant strain when compared to non splinted crowns. Cement retained prosthesis produce less peri implant strain when compared to screw retained prosthesis. Least strain was observed in cement retained splinted crowns.