Objective: To investigate the experience of timely thesis completion by the graduates of the Master of Health Professions Education (MHPE) program in Pakistan.Study Design: Qualitative interpretative study design.Settings: Riphah University Islamabad and HITEC-IMS Taxila.Duration: May 2018 to June 2019.Materials and Methods: Data was collected by semi-structured interviews. All interviews were carried out in person. Detailed notes were taken, and conversations were audio-recorded. Three authors analyzed data independently using iterative thematic analysis. Inconsistencies were resolved through discussion.Results: Two major themes out of five were identified: Intrinsic attributes of the graduates and the role of the supervisor. including sub-themes of intrinsic motivation, self-regulation, age of the participant, supervisor-trainee relationship, supervisor’s availability, supervisor’s commitment, personality traits of the supervisor. Periods of face-to-face contact sessions were considered to increase internal motivation during which participants believe to have greater self-regulation. Positive relationship with a committed supervisor who was readily available and had a friendly, yet professional attitude aided in the completion of the thesis on time while a supervisor lacking these traits posed challenges for the graduates.Conclusion: Several factors were identified which influenced thesis completion among the graduates of MHPE in Pakistan. The five major ones consisted of the following, 1) Research Project-Related Problems; 2) Support System; 3) Supervisor Guidance; 4) Attributes of the Researcher; 5) Conducive Research Environment. These results can help influence policies to evaluate and improve this program.

Objective: Rifampicin continues to be an effective drug for treatment oftuberculosis. A variety of drug reactions have been reported of which hepatotoxicity is wellknown. This study was conducted to investigate the effects of ascorbic acid as dietarysupplementation in case of Rifampicin induced hepatotoxicity. Data source: Animal house NIH(National Institute of Health). Study design: Randomized control trial. Materials and Methods:Thirty adult BALB/c mice weighing 30-60 grams were taken. They were kept under standardlaboratory conditions. Mice were randomized and divided into three groups A, B and C eachcontaining 10 mice. Group A was given Rifampicin 100 mg/kg body weight, group B wasadministered Rifampicin 100 mg/kg body weight along with ascorbic acid 500 mg/kg bodyweight orally and group C was given regular NIH lab diet for six weeks. Result: Liver specimens ofanimals given rifampicin showed formation of necrotic foci. Simultaneous administration ofascorbic acid significantly reduced histological changes induced by Rifampicin. Conclusions:Ascorbic acid has protective role against hepatotoxic effect of Rifampicin used in chemotherapyof tuberculosis in animal models.