No abstract

The title compound, C17H20N4S, generic name olanzapine, is an antipsychotic agent. The mol­ecule consists of three fused rings (benzene, diazepine and thio­phene) and an N‐methyl­piperazine substituent. The boat conformation of the central 1,5‐diazepine ring defines the overall shape of the mol­ecule. Two butterfly‐like mol­ecules form centrosymmetric dimers stabilized by C—H⋯π interactions between their cavities. The dimers are connected by intermolecular N—H⋯N, C—H⋯N and C—H⋯S hydrogen bonds.

ABSTRACT:The synthesis of 4-[3-(2-methylfuran-3-yl)-5-thioxo-1,2,4-triazolin-4-yl]

On a four series of 1-azolil-4-aryl/alkyl-

The title compound, C17H20N4S·CH4O, is an olanzapine 1:1 methanol solvate. A pair of olanzapine mol­ecules forms a centrosymmetric dimer with intermolecular C—H⋯π interactions. Intermolecular host–host N—H⋯N hydrogen bonds were not found. The guest mol­ecule is linked to host mol­ecules through O—H⋯N, N—H⋯O and C—H⋯O hydrogen bonds.