No abstract

To report the case of a 63-years-old female referred to the Oculoplastic Eyelid and Orbit Department of the ICO "Ramón Pando Ferrer" for two lesions in the left upper eyelid, the biggest one, a 20 mm nodule with a central ulcer full of debris and discharge. It was treated with antibiotics without improvement; a biopsy was carried out with a preliminary report of Mycosis Fungoides. A similar lesion appeared on the lower eyelid after surgery and was treated with perilesional HeberFERON injections, disappearing after three weeks. The final histopathology analysis revealed a Non-Hodgkin skin lymphoma with a high malignancy grade. Conclusions: Diagnosing Mycosis fungoides is difficult in early stages or atypical presentations. It's essential to know this disease and its stages to set it apart from entities with similar characteristics, aiming for an early diagnosis, treatment, and proper follow-up.