Objective: The current picture of cardiology is the result of great therapeutic advances and large clinical trials. Perhaps the most spectacular impact seen in recent decades has been among patients with coronary artery disease, whose life expectancy and quality of life have been profoundly altered by the introduction of percutaneous myocardial revascularization into practice. Design and method: The study was carried out in the Carol Davila Central Military Emergency University Hospital in Bucharest, on a group of patients with acute coronary syndrome with ST segment elevation, treated interventionally in our center through the RO-STEMI program. In the period 2015-2018, 1316 STEMI procedures were performed, of which 107 presented stent restenosis of various degrees, visually quantified by the angiographer. The presented study is observational, analytical, retrospective. This study can be considered a real world one, because the phenomenon of stent restenosis was studied and objectively correlated with clinical practice, reflecting the experience of our center. Results: HT represented an indicator present in the current study in a significant proportion - 80% of the patients in the study, being more frequent in men. A higher prevalence of arterial hypertension was observed in smoking patients. It has been noted that the presence of HT in overweight or HT associated with dyslipidemia increases the risk of AMI or other acute events (stroke). In the hypertensive patients studied, the percentage of major events was 20% higher, but without a statistically significant influence. The main risk factor incriminated in the determination and occurrence of the process of intraluminal proliferation resulting in intrastent restenosis was diabetes mellitus. In patients with DM, the percentage of events was 20% higher than in patients without DM. Diabetes, dyslipidemia, stent characteristics were independent risk factors for in-stent restenosis (p <0.05). Conclusions: In conclusion, for patients with risk factors indicating PCI, identification and personalized patient management are warranted to prevent in-stent restenosis. Long-term follow-up of patients with STEMI is essential both for their prognosis and for the individualization of this population through studies.

Background and aim. Modern society is experiencing an accelerated increase in the number of elderly people, to the detriment of children and young adults, in the context of declining birth rates, high adult mortality and increasing life expectancy due to advances in medicine. Cardiovascular diseases are becoming more common in the general population, representing the leading cause of death, being responsible for a third of the total number of deaths worldwide, and heart failure is the most common cause of hospitalization in patients over 65 years. Depression is one of the most common mental illnesses, presents different clinical pictures, which vary from person to person and in relation to age, being shown that there are somatic disorders due to depression, including cardiovascular disease. Materials and method. We studied 127 patients hospitalized in the Geriatrics Department of the Calarasi County Emergency Hospital, diagnosed with heart failure (HF), being divided into 2 groups: the first group, which included 63 patients with heart failure with mildly reduced ejection fraction and the second, which included 64 patients with heart failure with preserved ejection fraction. Results. The main risk factor present in the studied patients was dyslipidemia, which is present in 90% of patients with a mildly ejection fraction and in 88% of patients with a preserved ejection fraction. Hypertension was also present in 75% of patients in the first group and in 63% of those in the second group. Depression was present in 67% of patients with mildly reduced ejection fraction and in 64% of those with preserved ejection fraction. The degree of depression was higher among women, 11% of those with HF with mildly reduced ejection fraction and 14% of those with preserved ejection fraction had major depression. The degree of depression increases with age, patients over 80 years presented predominantly moderate-severe depression (41% of patients in the first group, and 50% in the second). Patients with NYHA class III heart failure had predominantly moderate-to-severe depression: 50% of patients with mildly reduced ejection fraction and 67% of those with preserved ejection fraction. Conclusion. Depression is an important independent risk factor for heart failure in the elderly patients. Due to the fact that the symptoms of the two pathologies are often similar, the diagnosis of depression can be difficult to make, which is why it should be investigated in all patients with heart failure. It is important to understand the peculiarities of the polypathology of the elderly, which often poses problems for the diagnosis and treatment of the clinician.

Objective: Depression and cardiovascular diseases are two common pathological entities in the elderly, their incidence increasing with advancing age. Clinicians have empirically observed that depression is an independent risk factor for hypertension, thus showing the need to demonstrate this hypothesis through clinical trials and also the correlation of depression with the occurrence of other cardiovascular diseases. Design and method: The study was carried out on 127 patients in the Emergency County Hospital dr. Pompei Samarian Calarasi, with cardiovascular disease, including hypertension, and/or depression. The presented study is observational, analytical, retrospective. The study group was randomized according to inclusion and exclusion criteria established prior to patient selection. Results: Hypertension is very common in the elderly. We observe a significant increase in blood pressure values with age. Patients at low, moderate, and high cardiovascular risk tend to have mild or moderate depression, and those at very high risk tend to have moderate or severe depression. Depression influences cardiovascular risk factors, favoring the increase of serum cholesterol and triglyceride values and favoring the decrease of serum HDL-cholesterol values, the influence of depression being statistically significant. The proportion of patients with hypertension who associate depression increases with increasing blood pressure values. To emphasize the importance of depression in hypertension, we excluded patients with metabolic syndrome. It has been observed that in these patients the association between depression and hypertension increases, emphasizing the fact that depression represents a cardiovascular risk factor. Studying the relationship between the severity of depression and the degree of arterial hypertension, it was observed that in patients with high blood pressure, the degree of depression is high. Conclusions: Considering all these aspects, we emphasize the importance of the correct and early diagnosis of depression in elderly patients, this being an important risk factor for cardiovascular diseases, including hypertension, often ignored in medical practice.