ABSTRACT Background. Chronic lymphocytic inflammation with perivascular contrast enhancement in the pons responsive to steroids (CLIPPERS) is a rare and relatively "new" pathology and MRI is highly important in its diagnosis. Clinical Case Description. Chronic lymphocytic inflammation with perivascular contrast enhancement in the pons responsive to steroids (CLIPPERS) is a rare and relatively "new" pathology and MRI is highly important in its diagnosis. Conclusion. MRI not only enables high-quality neuroimaging of CLIPPERS, it also allows avoiding invasive, traumatic diagnostic methods.