Since it was first detected, novel coronavirus disease rapidly spread, striking over 4 million people worldwide. 1 While adults with COVID-19 demonstrate a range of disease severity with 20% of infected adults being critically ill and an estimated fatality rate as high as 2%, children mostly suffer from a mild disease, only minority presenting with respiratory distress syndrome or multi-organ failure. [2][3][4] However, the role of infected children in spreading the virus to their older relatives and caregivers is yet to be determined.Many countries struggle to stave off the spreading of COVID-19 by using different strategies. In many countries, including Israel, authorities instructed the public to stay at home and to avoid visiting local clinics and hospitals as much as possible while using more telemedicine-based practice. 5 However, emergent medical situations continue to appear alongside the current outbreak and their diagnosis should still be made promptly. Delayed diagnosis and treatment of those common paediatric conditions may lead to significant morbidity that may overweigh the harm caused by COVID-19 infection.Appendicitis is the most common abdominal surgical emergency in paediatric population. 6 Early diagnosis of appendicitis

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This large longitudinal study provides new data on the decrease in eGFR with age. Accurate prediction of the natural rate of GFR decline might be used to distinguish between normally aging kidneys and those with chronic disease. This approach could avoid unnecessary diagnostic procedures in the former and facilitate appropriate treatment in the latter.