In this present work, the molecular interaction of the binary liquid mixture has been elucidated using ultrasonic technique. The recorded values of ultrasonic velocity (u), density (𝝆), viscosity (𝜼), and refractive index (n) for the experimented binary liquid mixtures of Ethanol with Benzene at 303 K are used to calculate the derived parameters such as adiabatic compressibility (𝜷 a ), free length (L f ), acoustic impedance (Z), free volume (V f ), molar volume (V m ), internal pressure (𝝅 i ), relaxation time (𝝉), Enthalpy (H), Electronic polarization (𝝐), Molar refraction (R m ), and the experimentally determined ultrasonic velocity have been compared with the with the computed values using different analytical models and empirical relations such as Nomoto's Theory (NOM), Free Length Theory (FLT), and Van Dael-Vangeal theory (VDV). The results are interpreted and reported to explain the behavior of benzene with ethanol.