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PurposeThis work aimed to study the drug delivery applications of iron oxide (Fe 3 O 4 ) nanoparticles with strontium (Sr) doping with varying molar ratios prepared by the co-precipitation route. The impact of increased strontium content on the particle size and magnetic properties was investigated. The impending of these nanoparticles for drug loading, drug release, and their respective cytotoxicity was also inspected. MethodsFirst, iron oxide nanoparticles were doped with various amounts of strontium, from 0.25, 0.50, and 0.75, to 1 mole using co-precipitation method. These synthesized nanoparticles were characterized by XRD, SEM, EDX, VSM, and FTIR for evaluating crystal structure, phase purity, morphology, composition, magnetic properties, and functional groups, respectively. Drug loading and drug release properties were determined using UV-vis spectroscopy, whereas MTT assay evaluated cytotoxicity. ResultsThe ndings con rmed the successful doping of iron oxide with strontium via XRD and EDX. SEM results con rmed spherical morphology for all and needle-like structure for 1 mole strontium doped sample. For VSM results, a single domain structure was established. It was also observed that the drug encapsulation e ciency increases with increased strontium content. Cytotoxicity results by MTT assay revealed increased cytotoxicity with increasing nanoparticle concentration, and ibuprofen-loaded nanoparticles showed higher cytotoxicity than unloaded nanoparticles at the same concentration. ConclusionThis study provided predominantly comparison of the cytotoxicity of ibuprofen-loaded and non-loaded nanoparticles on Hep-2 cancer cells at similar concentrations for the rst time for both Fe 3 O 4 particles and Sr-doped Fe 3 O 4 nanoparticles and enclosed the impact of increasing Sr doping content on Fe 3 O 4 nanoparticles.

Purpose This work aimed to study the drug delivery applications of iron oxide (Fe3O4) nanoparticles with strontium (Sr) doping with varying molar ratios prepared by the co-precipitation route. The impact of increased strontium content on the particle size and magnetic properties was investigated. The impending of these nanoparticles for drug loading, drug release, and their respective cytotoxicity was also inspected.Methods First, iron oxide nanoparticles were doped with various amounts of strontium, from 0.25, 0.50, and 0.75, to 1 mole using co-precipitation method. These synthesized nanoparticles were characterized by XRD, SEM, EDX, VSM, and FTIR for evaluating crystal structure, phase purity, morphology, composition, magnetic properties, and functional groups, respectively. Drug loading and drug release properties were determined using UV-vis spectroscopy, whereas MTT assay evaluated cytotoxicity.Results The findings confirmed the successful doping of iron oxide with strontium via XRD and EDX. SEM results confirmed spherical morphology for all and needle-like structure for 1 mole strontium doped sample. For VSM results, a single domain structure was established. It was also observed that the drug encapsulation efficiency increases with increased strontium content. Cytotoxicity results by MTT assay revealed increased cytotoxicity with increasing nanoparticle concentration, and ibuprofen-loaded nanoparticles showed higher cytotoxicity than un-loaded nanoparticles at the same concentration.Conclusion This study provided predominantly comparison of the cytotoxicity of ibuprofen-loaded and non-loaded nanoparticles on Hep-2 cancer cells at similar concentrations for the first time for both Fe3O4 particles and Sr-doped Fe3O4 nanoparticles and enclosed the impact of increasing Sr doping content on Fe3O4 nanoparticles.

Aim: Enhanced Magnetic, Dielectric, Optical and Ferro-Photovoltaic Properties of Barium Ferrite (BaFe2O4) Nanoparticles with Zn doping for Photovoltaic Applications Background: A complete examination of structural, magnetic, di-electric, photovoltaic, and optical properties of Zn doped barium ferrite particles has been performed, using X-ray diffraction (XRD), Scanning electron microscopy (SEM), Vibrating sample magnetometer (VSM), Impedance Analyzer, UV Visible spectroscopy, and Fluorescence spectrophotometer. Objective: The valuable results of magnetic, optical, and photovoltaic properties of Zn doped barium ferrites presented a novel idea for utilizing magnetic ferrites in photovoltaic applications. Method: Magnetic Ba1-xZnxFe2O4 (x = 0.0, 0.2, 0.3, 0.5) nanoparticles have been prepared by sol-gel auto combustion method. Result: The ferroelectricity and photovoltaic response were explored by Multiferroics system and Electrochemical impedance spectroscopy, respectively. The structure was detected orthorhombic with space group Pnma 3 for pure and Zn doped samples. The magnetization value for pure BaFe2O4 was increased from 1.4 emu/g to 15.3 emu/g for Ba0.7Zn0.3Fe2O4 sample. The ferroelectric behavior was reflected equally in pure BaF and Zn-doped samples. The photovoltaic results revealed an increase in photocurrent upon illumination in Zn = 0.3 sample. The dielectric properties showed direct relation with each other and supported ferroelectricity. The energy band gap value for pure barium ferrite (BaF) was reduced from 1.54 eV to 1.33 eV for Zn = 0.3 sample. The photoluminescence resulted in increasing emission intensity spectra for Zn = 0.3 and Zn = 0.5 at wavelength of 607 nm and 430 nm. Conclusion: The nanoparticles revealed an orthorhombic crystal structure with degraded particle size from 43-26.5 nm with increasing concentration of Zn doping. The same movement was followed by grain size from 245 to 33 nm. The lattice constant ‘a’, micro-strain, and dislocation density were increased. The growth of spherical nanoparticles and the desired composition of chemical bonds were verified by SEM and FTIR individually. The magnetization was upgraded from 1.4 emu/g to 15.32 emu/g, while coercivity was lessened with doping.