We propose a new model of cancer growth based on nonextensive entropy. The
evolution equation depends on the nonextensive parameter q. The exponential,
the logistic, and the Gompertz growth laws are particular cases of the
generalized model. Experimental data of different tumors have been shown to
correspond to all these tumor-growth laws. Recently reported studies suggest
the existence of tumors that follow a power law behavior. Our model is able to
fit also these data for q<1. We show that for q<1, the commonly used
constant-intensity therapy is unable to reduce the tumor size to zero. As is
the case of the Gompertzian tumors, for- q<1 a late-intesification schedule is
needed. However, these tumors with q<1 are even harder to cure than the
Gompertzian ones. While for a Gompertzian tumor a linearly-increasing cell-kill
function is enough to reduce the tumor size to zero following an exponential
decay, in the case of tumors with q<1, the exponential decay is obtained only
with an exponentially increasing cell-kill function. This means that these
tumors would need an even more aggressive treatment schedule. We have shown
that for Gompertzian tumors a logarithmic late-intensification is sufficient
for the asymptotic reduction of the tumor-size to zero. This is not the fastest
way but it is more tolerable for patients. However for the tumors with q<1 we
would need at least a linearly increasing therapy in order to achieve a
similarly effective reduction. When q>1, tumor size can be reduced to zero
using a traditional constant-intensity therapy.Comment: 5 figure
We analyze propagation of acoustic vortex beams in longitudinal synthetic magnetic fields. We show how to generate two field configurations using a fluid contained in circulating cylinders: a uniform synthetic magnetic field hosting Laguerre-Gauss modes, and an Aharonov-Bohm flux tube hosting Bessel beams. For non-paraxial beams we find qualitative differences from the well-studied case of electron vortex beams in magnetic fields, arising due to the vectorial nature of the acoustic wave's velocity field. In particular, the pressure and velocity components of the acoustic wave can be individually sensitive to the relative sign of the beam orbital angular momentum and the magnetic field. Our findings illustrate how analogies between optical, electron, and acoustic vortex beams can break down in the presence of external vector potentials. arXiv:1908.08278v1 [physics.class-ph]
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