A series of 9-[(aminoalkyl)thio]-9H-xanthenes (3-6) and 5-[(aminoalkyl)thio]-5H-[1]benzopyrano[2,3-b]pyridines (7-10) possessing gastric antisecretory activity in the rat and dog is described Many of the compounds possessed good activity in the pylorus-ligated rat and several inhibited histamine-stimulated gastric acid secretion in the dog. The mechanism of acid secretion inhibition is not related to anticholinergic or histamine (H2) receptor antagonism.

Reaction of benzene or substituted benzenes with antimony pentafluoride gives, dependent on the aromatics and reaction conditions, diaryltrifluorostibines, triaryldifluorostibines, or polycondensed products.The mechanism of the Friedel-Crafts metalation reaction, a suitable new method for the preparation of arylantimony compounds, is discussed.We recently observed the fluoroantimonic acid induced alkylation of benzene and substituted benzenes with alkanes.3 We also studied previously the protonation of benzene and alkylbenzenes in the same acid.4 In the course of our work it became ob-(1)

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Aus Alkoholen oder Phenolen erhält man durch Umsetzung mit Kaliumcarbonat/Kaliumiodid und anschließend mit dem Chlorid (I) die im Formelschema angegebenen N,N‐Dipropylalkoxyacetamide.

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