HighlightsAflatoxins toxicity model has been developed.Tracing aflatoxins concentration in foods and feeds at various stages is shown.The need to use experimental data is suggested.Satisfactory harmonization of acceptable threshold levels of aflatoxins in foods and feeds could be drawn.
Nigeria is second to South Africa with the highest reported cases of COVID-19 in sub-Saharan Africa. In this paper, we employ an SEIR-based compartmental model to study the transmission dynamics of SARS-CoV-2 outbreaks in Nigeria. The model incorporates a different group of populations (that is high- and- moderate risk populations) and is used to investigate the influence on each population on the overall transmission dynamics.The model, which is fitted well to the data, is qualitatively analyzed to evaluate the impacts of different schemes for controlstrategies. Mathematical analysis reveals that the model has two equilibria; i.e., disease-free equilibrium (DFE) which is local asymptotic stability (LAS) if the basic reproduction number (
) is less than 1; and unstable for
, and an endemic equilibrium (EE) which is globally asymptotic stability (LAS) whenever
.Furthermore, we find that the model undergoes a phenomenon of backward bifurcation (BB, a coexistence of stable DFE and stable EE even if the
). We employ Partial Rank Correlation coefficients for sensitivity analyses to evaluate the model’s parameters. Our results highlight that proper surveillance, more especially movement of individuals from high risk to moderate risk population, testing, as well as imposing other NPIs measures are vital strategies for mitigating the COVID-19 epidemic in Nigeria.Besides, in the absence of an exact solution for the proposed model, we solve the model with the well-known ODE45 numerical solver and the effective numerical schemes such as Euler (EM), Runge-Kutta of order 2 (RK-2), and Runge-Kutta of order 4 (RK-4) in order to establish approximate solutions and to show the physical features of the model. It has been shown that these numerical schemes are very effective and efficient to establish superb approximate solutions for the differential equations.
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