Introduction: In the context that even defined as a reference in health care, the treatment to end the use of tobacco has in the adherence your major challenge, asks about the panorama of promising computational technologies. The study aimed to summarize the evidence, through a systematic review, about the overview of these tools in the adherence of smoking cessation therapy. Method: The databases, Medline (via PubMed), Cochrane Libray, Scopus, Web of Science and Lilacs, were consulted using a search strategy based on health condition and intervention of interest. Study selection, carried out in two steps (titles and abstracts and, later, full text), quality assessment and data extraction were performed in duplicate with disagreement in charge a third reviewer. Results: Twelve clinical trials with a predominantly female population, with spotlight for age group over 35 years old, were included in the review. Most of them, characterized by publication after 2013 and in the North American subcontinent, with follow-up time of less than four months. The study sample sizes were comprehensive, with a median of 350 participants and an average of 2,831.75. The definition of adherence to smoking treatment was different between studies, but it was possible to make comparability in more than 90% of the groups investigated. Even with the decrease inherent in the smoking population, the outcome of interest (adherence to smoking treatment) in computational technologies was propitious, as well as in the treatment groups that associated it with pharmacotherapy. Conclusion: The panorama was favorable to adherence to smoking cessation treatment conducted by computational technologies.
BACKGROUNDTakayasu's arteritis (TAK) is a large vessel vasculitis that mainly affects aorta and its primary branches. Inflammation causes thickening of the arteries walls, which may lead to stenosis, occlusion or dilation. However, inflammatory pseudotumor of the carotid artery has never been described in TAK. The aim of this report is to describe the case of a patient diagnosed with TAK evolving with a pulsatile, inflammatory neck mass. CASE REPORTWe herein report a case of a 31-year-old male patient, who presented with asymmetrical blood pressure and pulses in the upper limbs, left arm claudication, and elevated markers of inflammation. Computed tomography angiography (CTA) confirmed the diagnosis of type V TAK. He was initially treated with prednisone and azathioprine. However, azathioprine was discontinued due to gastrointestinal intolerance and was replaced by methotrexate. During follow-up, he evolved with disease flare (worsening of claudication and reduction in pulse of the left upper limb, elevation of inflammatory markers and worsening of left subclavian artery obstruction). A new induction therapy was prescribed with intravenous pulse therapy with methylprednisolone and cyclophosphamide, maintaining disease remission for 8 months. After that, a new disease flare occurred, and biological treatment was proposed. However, he had irregular medical follow-up and was unable to obtain the prescribed medications for several months. One month prior to the last medical visit, he evolved with clinical worsening and developed a fast-growing, pulsatile, right painful neck mass, associated with carotidynia, aphonia and systemic symptoms. He was referred to inpatient care for further investigation and respiratory monitoring. An urgent CTA was performed and revealed a large inflammatory vascular parietal thickening of the right carotid artery without evidence of aneurysmal formations, thrombosis or dissection, suggestive of inflammatory pseudotumor of the carotid; no evidence of external compression of upper airways was found. MRI showed the same findings of CTA. Videolaryngoscopy was performed and was normal, suggesting a psychogenic etiology to the aphonia. He was treated with pulse therapy with methylprednisolone and cyclophosphamide, and the mass promptly started to reduce. Biopsy was not feasible, since the mass almost disappeared within few days, due to the excellent response to clinical treatment. CONCLUSIONThis is the first report of inflammatory pseudotumor of the carotid artery in a patient diagnosed with TAK. Adequate pharmacological treatment and adherence to therapy may ensure better outcomes and prevent complications.
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