Objectives: The aim of the present study was to analyze the possible changes caused by the maternal ingestion of different types of fatty acids during pregnancy in the pro-inflammatory state in the odontogenesis of fetuses. Subject and Methods: For this, 24 jaws (n=6 per group) of Wistar rats were collected on the 20th day of intrauterine life. Mothers were separated on the first day of pregnancy into 4 groups according to diet, as described below: Control group (C) – diet with soy oil as a source of fat, group (S) – diet with rich lard in saturated fatty acids, group (T) – diet with vegetable fat rich in trans-saturated fatty acids and group (PUFA) – diet with fish oil, rich in polyunsaturated fatty acids. Results: In the microscopic analysis, the results showed no alterations in the tissue development of the teeth between the groups with different lipid diets (T, S and PUFA) when compared to the control group (C) and the immunohistochemical analysis for the expression of JAK2, STAT3, P-STAT3, SOCS3 and IL-6 showed no statistically significant difference (p>0.05) compared to the control group. However, there were changes (p<0.05) between the T group and the PUFA group in the expression of JAK2. Conclusion: Thus, lipid consumption in the maternal diet remains a topic to be explored in embryonic development, despite not causing morphological changes to the tooth germ of rats.