ObjectiveTo describe and compare the annual success rates of medical treatment in the analyzed period and to evaluate the associated factors.MethodsRetrospective study with 158 women with tubal pregnancy followed up over 17 years. Statistical analysis was performed using the Cochran‐Armitage test, the χ2 test, Mann–Whitney test, and multiple logistic regression.ResultsThe success rate was 47.4%. There was a trend of significant change in the success rate of clinical treatment over time (Z = 2.01, P = 0.044); it was associated to undergoing treatment between 2012 and 2017 (P = 0.028), the absence of abdominal pain (P = 0.020), receiving a higher dose of methotrexate (P < 0.001), and less time hospitalized (P < 0.001). In the final statistical model, we observed that receiving a higher dose of methotrexate (P = 0.025, odds ratio [OR] 1.03, 95% confidence interval [CI] 1.00–1.06), having a low serum β‐HCG concentration before treatment (P = 0.003, OR 0.87, 95% CI 0.79–0.95), and not having abdominal pain (P = 0.004, OR 4.26, 95% CI 1.61–11.28) were factors associated with a higher chance of successful clinical treatment for tubal pregnancy.ConclusionA greater chance of success was observed among women undergoing clinical treatment from 2012 onwards, who used higher doses of methotrexate, were asymptomatic at admission, and had low concentrations of β‐hCG.

Objective To evaluate the use of different treatment options for ectopic pregnancy and the frequency of severe complications in a university hospital. Methods Observational study with women with ectopic pregnancy admitted at UNICAMP Womeńs Hospital, Brazil, between 01/01/2000 and 12/31/2017. The outcome variables were the type of treatment (first choice) and the presence of severe complications. Independent variables were clinical and sociodemographic data. Statistical analysis was carried out by the Cochran–Armitage test, chi-square test, Mann–Whitney test and multiple Cox regression. Results In total 673 women were included in the study. The mean age was 29.0 years (± 6.1) and the mean gestational age was 7.7 (± 2.5). The frequency of surgical treatment decreased significantly over time (z = -4.69; p < 0.001). Conversely, there was a significant increase in the frequency of methotrexate treatment (z = 4.73; p < 0.001). Seventy-one women (10.5%) developed some type of severe complication. In the final statistical model, the prevalence of severe complications was higher in women who were diagnosed with a ruptured ectopic pregnancy at admission (PR = 2.97; 95%CI: 1.61–5.46), did not present with vaginal bleeding (PR = 2.45; 95%CI: 1.41–4.25), had never undergone laparotomy/laparoscopy (PR = 6.69; 95%CI: 1.62–27.53), had a non-tubal ectopic pregnancy (PR = 4.61; 95%CI: 1.98–10.74), and do not smoke (PR = 2.41; 95%CI: 1.08–5.36). Conclusion there was a change in the first treatment option for cases of ectopic pregnancy in the hospital during the period of analysis. Factors inherent to a disease that is more difficult to treat are related to a higher frequency of severe complications.

Tuberculose peritoneal é uma doença de difícil diagnóstico e representa cerca de 1-2% das formas desta infecção. Sua apresentação clínica é variada e inespecífica, sendo dor abdominal e febre os achados mais frequentes. Relata-se caso de paciente do sexo feminino, de 48 anos, com ascite, febre e perda ponderal, cujo diagnóstico inicial era câncer de ovário com carcinomatose peritoneal. A investigação adicional com exames laboratoriais e biópsia de omento estabeleceram o diagnóstico de tuberculose peritoneal. Não havia tuberculose pulmonar. Foi feito tratamento específico com resposta satisfatória. O presente trabalho objetiva ressaltar que, dentre as diferentes patologias que acometem o peritônio, a peritonite tuberculosa deve ser um diagnóstico considerado, principalmente na presença de ascite e quadro abdominal inespecífico e discutir os principais achados e a abordagem investigativa.

Background: to evaluate the use of different treatment options for ectopic pregnancy and the frequency of severe complications in a university hospital. Methods: observational study with women with ectopic pregnancy admitted at UNICAMP Women´s Hospital, Brazil, between 01/01/2000 and 12/31/2017. The outcome variables were the type of treatment (first choice) and the presence of severe complications. Independent variables were clinical and sociodemographic data. Statistical analysis was carried out by the Cochran–Armitage test, chi-square test, Mann–Whitney test and multiple Cox regression. Results: 673 women were included in the study. The mean age was 29.0 years (±6.1) and the mean gestational age was 7.7 (±2.5). The frequency of surgical treatment decreased significantly over time (z=-4.69; p<0.001). Conversely, there was a significant increase in the frequency of clinical treatment (z=4.73; p<0.001). Seventy-one women (10.5%) developed some type of severe complication. In the final statistical model, the prevalence of severe complications was higher in women who were diagnosed with a ruptured ectopic pregnancy at admission (PR=2.97; 95%CI: 1.61–5.46), did not present with vaginal bleeding (PR=2.45; 95%CI: 1.41–4.25), had never undergone laparotomy/laparoscopy (PR=6.69; 95%CI: 1.62–27.53), had a non-tubal ectopic pregnancy (PR=4.61; 95%CI: 1.98–10.74), and do not smoke (PR=2.41; 95%CI: 1.08–5.36). Conclusion: there was a change in the first treatment option for cases of ectopic pregnancy in the hospital during the period of analysis. Factors inherent to a disease that is more difficult to treat are related to a higher frequency of severe complications.