Chronic crack of the lip has a high prevalence among young people in subarctic climates. The disease relapses and remissions. Linear cracks on the lips cause pain, discomfort, defects, aesthetics, cracks are completely constantly observed without complex treatment and prevention during exposure to adverse environmental conditions. The meteorological factor is a trigger mechanism for the development of chronic recurrent lip cracks in the subarctic climate. Cold wind and high sweetness destabilize the barrier function of the lip epithelium, reduce the activity of intercellular lipids. The study involved 68 male patients aged 18 to 28 years with an established diagnosis of chronic recurrent lip crack. In patients, adverse meteorological conditions were carriers of etiological diseases according to the anamnesis. At the primary medical appointment, the doctor treated chronic cracks with 0.05% chlorhexidine bigluconate, took an anamnesis, and took a complete blood count. Patients were divided into 3 groups of average manifestations of diseases (defect size, duration and nature of the manifestation). Within 14 days, patients had to adhere to the local therapy plan: group 1 used a cream based on 0.1% mometasone for 7 days, cocoa butter 3 times a day for the next 7 days, group 2 - the use of 20% propolis ointment 2-3 times a day, group 3 - local sea buckthorn oil 5 times a day. All patients were given recommendations and prescribed vitamin therapy for 2 months: AEvit and Combilipen. The subjects were tested to determine the interest in treatment on the 7th day. We evaluated the results of treatment on days 7, 14 and 30. Based on the results of the study, we concluded that, regardless of the interest in treatment, the best results were shown by treatment according to the group 1 scheme with the use of glucocorticoids. The rest of the study participants had results ranging from complete epithelialization and remission to no sign of improvement, depending on the level of interest in treatment. The treatment of a chronic lip crack requires an individual and comprehensive approach and the patient's obligatory interest in treatment. Patients should definitely use lipids as part of hygienic lipsticks during the remission period. This local prophylaxis helps restore the lipid matrix of the stratum corneum and maintain the lipid barrier of the red border of the lips from the effects of adverse meteorological factors of the subarctic climate.

Traumatization of the lips by adverse meteorological conditions during the cold season predisposes to the development of meteorological cheilitis, which is often ignored by doctors. The diagnosis can be complicated by the addition of an infectious agent against the background of a chronic violation of the integrity of the tissues, and with a long course it can turn into obligate forms of precancerous diseases of the lips. In the development of meteorological cheilitis in residents of the Far North, a special role is played by "polar" metabolism and a weakened antioxidant defense of the body, which is the most important link in the pathogenetic mechanism for the development of meteorological cheilitis in the population. The purpose of this study is to improve the system of diagnosis and treatment of meteorological cheilitis, taking into account etiopathogenetic features. Material and methods. The study included patients with a confirmed diagnosis of meteorological cheilitis without a burdened anamnesis. After collecting an anamnesis, examination, general and local therapy was prescribed. Before and after treatment, a biochemical study of the content of vitamins A, E, D in the blood serum was carried out. Results and discussion. An analysis of the content of vitamin D before treatment indicates a low level of vitamin D in more than 50% of the subjects, the results of the remaining patients are in the range of the lower limit of the reference values. The content of vitamins A and E in the serum of venous blood is in the acceptable range. 2 months after treatment, the content of vitamin D in the blood serum of all patients rose to normal levels. Conclusions. Complex local and general therapy led to the neutralization of the clinical manifestations of meteorological cheilitis in 100% of patients. A scheme for the prevention of meteorological cheilitis in residents in adverse climatic conditions has been developed.