A list of species was prepared by examining 2,772 specimens deposited in 10 Brazilian collections. A total of 499 arctiines were recorded in 30 municipalities, 1.4% of these species are endemic to the state of Santa Catarina. The most species-rich localities were Joinville, São Bento do Sul, Seara, and Brusque. Only 15 nights of samplings were performed in the 21st century. The deciduous forest has been extremely subsampled with respect to Arctiinae moths compared to the other types of vegetation found in the state of Santa Catarina. For a more comprehensive diagnostic of the species richness and composition of Arctiinae moths in Santa Catarina state, aiming conservation strategies of vulnerable habitats and taxa, samplings are needed in many municipalities in the state, especially in areas of deciduous forest and grasslands.