Medium chain triglyceride (MCT)-based diet, total parenteral nutrition (TPN) and repeated paracentesis are considered as supportive management for congenital chylous ascites (CCA). TPN is considered where therapy with oral MCT is poorly tolerated by the patient especially young infant with unstable hemodynamic. Surgery is recommended when medical therapy fails. Herein, we report a 2½-month-old infant with CCA, treated successfully with octreotide intravenous infusion after the initial failure to response to conventional conservative therapy with MCT-enriched formula and paracentesis.

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Tuberous sclerosis is a neurocutaneous autosomal-dominant disorder, presents with highly variable clinical manifestation and affects multiple organ system. Its manifestation in neonate is poorly described. We report a case of intractable neonatal seizure with multiple hypopigmented patch. Neuroimaging of brain shows classical cortical tubers and subependymal nodule suggestive of tuberous sclerosis in newborn. Hence tuberous sclerosis should be considered as an etiology of neonatal seizure and neuroimaging should be performed when other common causes of neonatal seizure have been excluded.

Background: Ineffective erythropoiesis and excessive red blood cell transfusions are the major source of iron overload in case of thalassemia major patients. It is mainly accountable for the growth retardation, morbidity, and mortality in patients with beta thalassemia major. The availability of effective iron chelators and proper knowledge regarding the iron toxicity can significantly improve the rate of survival in thalassemia patients. Aims and Objectives: The study was done to compare the efficacy and safety of the deferiprone (DFP) with deferasirox (DFX) in regulating the growth pattern among the thalassemia major patients. Materials and Methods: The height and weight were plotted on the World Health Organization recommended growth charts for 0–5 years and 5–19 years old boys and girls during the follow-up visits. Comparison between the role of DFP versus DFX was evaluated by t-test. Results: There is no statistically significant (P=0.11 in males and P=0.06 in females) difference between DFP versus DFX while considering height velocity. A similar observation was obtained in case of weight velocity (P=0.78 in males and P=0.56 in females) and basal metabolic index (BMI) index (P=0.44 in males and P=0.53 in females). Conclusion: Both DFX and DFP have no significant correlation in regulating the height, weight, and BMI of thalassemia children.