Experiments are described in which domestic rabbits were deliberately subjected to a daily 3-4 hours noise regime (65 dB) for 18, 28, 40 and 50 days, to determine its effects on the blood. Noise exposure to rabbits caused a general increase in its biochemical parameters such as urea, uric acid, creatinine, cholesterol, and triglycerides, while glucose level decreased significantly. Our results indicate a general decrease of total protein, albumin and globulin levels. The results indicated that noise exposure at split dose could be harmful. It found that recovery period were able to alleviate some of those harmful changes.

Histological and histochemical changes in the livers of 40 adult male albino rats (Rattus norvegicus) were studied at different intervals following methyl alcohol administration. The animates were divided into three groups. Methanol was administrated by oral a intubation in two doses (1m1/Kg. body weight and 2m1/Kg. body weight, respectively) for twenty consecutive days. Then the animals were killed after different periods of time (5, 10 and 20 days). The changes appeared to be time and/or dose dependent. Early signs of hepatic changes were characterized by hydropic degeneration, nuclear pyknosis, erosion of the endothelial lining of the blood vessels, vascular congestion and internal haemorrhage. Degenerative hepatic cells were seen invaded by inflammatory infiltrative cells. Maximum signs of deterioration were detected when 2m1/Kg. body weight was given. The first dose of methanol (1m1/Kg. body weight) caused depletion of liver glycogen, lipids, total proteins, proteins containing NH group, nucleic acids contents, and succinate dehydrogenase (SDH). Also, it caused a significant elevation of alkaline and acid phosphatase activities. The second dose of methanol (2m1/Kg. body weight) showed stronger effects on the 10th and 20th days of administration.