Objectives The aim of this study was to identify the demographic characteristics of chondrosarcoma (CS) and prognostic factors affecting survival. Patients and methods A total of 87 patients (45 males, 42 females; median age: 51.3 years; range, 19 to 77 years) with CS treated in our clinic between January 2007 and June 2020 were retrospectively analyzed. Demographic characteristics, whether it was primary/secondary, tumor location, histopathological features, tumor grade and stage, clinical follow-up period, surgical treatment methods, use of radiotherapy and chemotherapy, and the presence of local recurrence and metastasis in the postoperative period were recorded. The relationship of these factors with prognosis was analyzed and survival rates were compared. Results Histological subtype, tumor grade, pathological stage and presence of metastasis were defined as independent predictors in both overall survival and disease-free survival analysis of CS. Overall and disease-free five-year and 10-year survival rates were found to be the highest in the clear cell chondrosarcoma group. While mortality increased in the first five years in the patient groups with histological Grade 2 and 3, all groups were followed in a balanced manner over time. The mortality rate in the group with metastatic disease (M2) was approximately four times higher than the other groups at 10-year follow-up. According to the surgical margins, we found that the five-year survival rates of the R1 (marginal resection) and R2 (residual tumor) groups were similar, with the highest rate being in the R0 (wide resection) group with 78.3%. In multivariate analysis, only grade and stage had a significant association with disease-specific survival. Surgical resection combined with adjuvant radiotherapy was found to increase survival in both overall and disease-free survival of patients with dedifferentiated chondrosarcoma compared to other treatments. Conclusion Histological subtype, grade, stage and presence of metastasis were the independent prognostic factors for survival in CS. However, marginal resection was a risk factor for local recurrence (LR), but there was no significant difference in overall survival in patients with or without LR. Although it is not significant, radiotherapy could increase survival in dedifferentiated CS variants.
Introduction: In recent years, the internet and social media have become the primary source for patients to research their medical conditions. Given the billions of links that result from research, it has become increasingly important how medically high quality the priorities of the search algorithms are. This study aims to examine the medical quality of videos on social media. Material and Method: A new Gmail account was never used, and Facebook, Instagram, Twitter, and YouTube accounts were opened. The word “knee replacement” was searched via social media. The video duration, daily views, total views, number of likes, source, and shared content were recorded. The parameters were statistically evaluated using the scales JAMA, GQS, DISCERN, and VPI to measure the quality of the medical posts. Results: Correlations were found between JAMA, GQS, and DISCERN. No correlation between the VPI scales with other scales was found. It was found that the promotional content in videos other than Instagram was very high (56–70%). Academics and healthcare workers produced greater quality content than other groups. There is a clear dominance of healthcare practitioners on Instagram. The most shared content was informative, depending on the content. The most frequent users were alternative health practitioners. While YouTube had the highest JAMA, GQC, and DISCERN (2.98, 3.18, 37.5) scores, the lowest VPI (0.761) score was found. Discussion and Conclusions: It has been shown that Instagram and Twitter are not the right places to share videos with medical content. However, everyone should remember that Instagram is the best place to share short but popular videos. YouTube and Facebook are available resources to share videos of better medical quality with a higher score than others. We can say that the most reliable medical sources are Facebook and YouTube videos of physicians and medical staff.
Aim: Electric scooters (e-scooters) are widely used as alternative vehicles worldwide. These light vehicles do not need a license to drive, and it is also popular among vehicles under the age of 18 among users in Turkey. This is a new term in the literature since there is an increase in accidents resulting from this overuse. This study aims to reveal the patterns and severity of orthopedic injuries resulting from using an e-scooter, especially in the pediatric population.Patients and methods: Patients who were admitted to the university hospital emergency department due to using an e-scooter and had fractures were retrospectively analyzed. Demographic data, admission times, injury mechanisms, and fracture patterns of the patients were documented.Results: Forty-nine (49.4%) of 99 patients were under 18, and 50 (50.6%) were over 18. It is seen that 58.5% (58 patients) had an accident by falling spontaneously, 37.3% (37 patients) collided with vehicles in traffic, and 4.2% had an accident by colliding with a standing object. While 59.5% of the upper extremity fractures are seen, 27.2% are lower extremity fractures. Multiple fractures were observed in 13.3%.Conclusion: Pediatric population frequently uses these alternative means of transport. The pediatric group usually had upper extremity injuries, while adults mostly had lower extremity injuries. Care must be taken when children are drivers of e-scooters.
Gorham-Stout disease causes gradual bone loss (osteolysis) due to an abnormal overgrowth of lymphatic vessels. This rare disease is usually seen in younger people. The etiopathology of Gorham-Stout disease remains unclear. The disease is pathologically characterized by the proliferation of the vascular or lymphatic vessels and, finally, bone matrix destruction. These pathological changes lead to the presence of massive osteolysis on plain radiographs. Thus, plain radiograph findings may lead physicians to consider tumoral conditions, especially metastasis. There are several other conditions on the differential diagnosis list of massive osteolysis, such as metabolic, infectious, malignant, and immunological conditions. After excluding all possible disorders, the disease can be considered in the differential diagnosis. The treatment of the disease is symptom-based, but there is no consensus. Pharmacological methods should be considered first-line treatment. If there is no regression in the course of the disease despite pharmacological treatment, radiotherapy and resection arthroplasty are the treatment of choice in the later stages. In this case report, we present a case of Gorham-Stout disease, which was treated by pharmacological methods. During the one and half year follow-up, the local control of the disease was achieved without any surgical intervention.
Osteoid osteoma (OO) kemiğin sık görülen benign kemik tümörlerinden biridir. Tedavide amaç nidusun çıkarılması ve ağrının giderilmesidir. Yazımızda tolere edilemeyen ağrılı osteoid osteomalı hastalara uyguladığımız cerrahi tedavi sonuçlarının incelenmesi amaçlanmıştır. Yöntemler: Kliniğimizde OO tanısıyla cerrahi tedavi uyguladığımız ve son kontrolleri yapılan 39 hasta çalışmaya dahil edildi. Hastaların klinik özellikleri, radyolojik bulguları, cerrahi tedavi yöntemi ve başarısı incelendi. Bulgular: Otuz dokuz hastanın 24'ü erkek, 15'i kadın ve yaş ortalaması 19,6 yıl olarak bulundu. En sık femur (17) ve tibiada (11) tutulum tesbit edildi. Direkt grafide 39 hastadan 18'inde, bilgisayarlı tomografi (BT) çekilen 32 hastadan 28'inde, manyetik rezonans görüntüleme (MRG) ile incelenen 24 hastadan 11'inde nidus gösterildi. Kemik sintigrafisi çekilen 18 hastadan 10'unda nidus tesbit edildi. Otuz dokuz hastadan dördünde nüks görüldü, üçüne tekrar cerrahi tedavi uygulandı. Sonuç: Tanı için anamnezde ağrının özelliklerinden ve radyolojik olarak özellikle ince kesit BT'de nidusun görüntülenmesinden faydalanılmalıdır. Osteoid osteoma tedavisinde nidusun tamamen çıkarılması gereklidir. Tedavinin başarılı olduğu ağrının geçmesi ve radyolojik olarak nidusun çıkarıldığının gösterilmesi ile mümkündür.
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