The verification of analytical methods is a requirement of the standard NF EN ISO 15 189. It consists of evaluating the performance of an analytical method according to a well-defined protocol and then comparing it with pre-established analytical objectives. The mastery of this approach must be the concern of any biologist. Through this work we present the results of the protocol of verification of the method of determination of microalbumin by comparing two automats: Alinity ci ® and Architect ci-8200® Abbott. Microalbumin monitoring in urine is an important element in the treatment of diabetes mellitus types I and II. It can also be used to predict diabetic nephropathy, which is the leading cause of death in people with insulin-dependent diabetes.

In addition to using the most up-to-date analytical technique, a thorough preparation phase must come first in order for the biological examination results to be reliable. The pre-analytical phase is this important step. We decided to conduct a prospective and descriptive study within central Laboratory department of the Mohammed VI University Hospital of Oujda with the goal of evaluating the pre-analytical phase in order to take action on the primary causes of pre-analytical nonconformity. In the course of observing 310 samples, we found 214 instances of pre-analytical nonconformities, of which 62 had to do with the prescription sheet, 62 with patient preparation, 31 with equipment preparation, 37 with the sampling procedure, 22 with waste management. Following the identification of these nonconformities in the hospital services under review, a multitude of corrective and preventive measures were taken in order to meet the standards of International Standard ISO15189 and to ensure the best possible patient care. Indeed, these key initiatives include audits, ongoing education, staff awareness and support.