Breast cancer is reported to rank fifth among all types of cancer with a case of death of 6.6%. In the Central Kalimantan region, early examinations of cancers including breast cancer were carried out and 247 tumors in the breast were identified (1.76%). Kelakai (Stenochlaena palustris) as one of the typical plants of Kalimantan which contain natural chemical constituents has been reported to be effective as an anti-inflammatory and antioxidant, so that with this potential can be developed to overcome diseases associated with it, one of them is breast cancer. This study aimed to examine the cytotoxicity of MCF-7 breast cancer cells using ethanol extract. The cytotoxicity assay of kelakai extract against MCF-7 cells conducted in vitro by the MTT reduction method. The variation of concentration used is 1000; 500; 250; 125; 62.5; 31.5; and 15.625 µg/ml, doxorubicin as a positive control was performed in a concentration of 1 μg / ml. The results of the cytotoxicity assay showed that the kelakai extract had a toxic effect on MCF-7 cells with an IC50 value of 493.57 µg / ml.

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BACKGROUND: Increased coverage antenatal care (ANC) occurring in developing countries do not guarantee the success of the ANC, it is because a high rate of maternal and neonatal mortality associated with inadequate and poor quality of maternal care, including ANC. AIM: This study aimed to find out the differences in the quality of ANC in rural and urban primary health centers in Jeneponto Regency. METHODS: This research aims to determine the different quality of ANC at urban and rural puskesmas (public health center), Jeneponto regency. The type of the research was observational analysis with cross-sectional design. There were 139 fixed samples of rural and urban pregnant women visiting the puskesmas, from October 2015 to May 2016. The samples were selected using stratified random sampling method from two puskesmas of each area. RESULTS: The results indicate that 52.6% of ANC quality is categorized bad. There is different ANC quality based on body weight, the height of fundus uteri, and administration of Fe tablet (0.038, 0.029, and 0.006). There is no difference of antenatal quality based on body height, LILA, fetus’ heartbeat, fetus presentation, blood type and Hb, and immunization of TT (0.068, 0.501, 1.000, 1.000, 0.133, 0263, and 0530). Blood pressure is not analyzed. CONCLUSION: There are three components that show differences in rural and urban health centers, namely, weight measurement, fundal height measurement, and FE tablet administration. As for the components of height measurement, assessment of nutritional status (MUAC), fetal presentation, examination of fetal heart rate, administration of TT immunization, and examination of blood type and hemoglobin. The component of blood pressure measurement was not included in the statistical test because all respondents received the examination.

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