The most widely used qualitative research methodologies are grounded theory and phenomenology. Both methodologies have expanded over time to several adaptations aligning with different paradigms, complex philosophical assumptions, and varying methodological strategies. Novice researchers either mistakenly mix the strategies of both methodologies or blend specific assumptions of methodologies’ different adaptations. Choosing the appropriate methodology and the specific adaptation in line with research inquiry and congruent with the researchers’ worldview is crucial in undertaking rigorous qualitative study. To date, there is limited literature that compared and contrasted the varying philosophical underpinnings of the two methodologies’ different adaptations. The purpose of this methodological paper is to provide a general overview of the two methodologies’ different adaptations to illustrate how they differ in approach. By immersing into the origins, philosophical assumptions, and utility of the two methodologies’ adaptations, novice researchers will develop a general overview of the foundations that support those specific adaptations. Finally, the considerations in choosing a specific adaptation of a methodology are discussed and applied by underpinning a research question on the care experiences of patients in the Accountable Care Unit. Thus, this methodological paper may assist novice researchers in deciding which specific adaptation of the two methodologies is the appropriate qualitative methodology for their research.