The complex process of biological aging, as an intrinsic feature of living beings, is the result of genetic and, to a greater extent, environmental factors and time. For many of the changes taking place in the body during aging, three factors are important: inflammation, immune aging and senescence (cellular aging, biological aging). Senescence is an irreversible form of long-term cell-cycle arrest, caused by excessive intracellular or extracellular stress or damage. The purpose of this cell-cycles arrest is to limit the proliferation of damaged cells, to eliminate accumulated harmful factors and to disable potential malignant cell transformation. As the biological age does not have to be in accordance with the chronological age, it is important to find specific hallmarks and biomarkers that could objectively determine the rate of age of a person. These biomarkers might be a valuable measure of physiological, i.e. biological age. Biomarkers should meet several criteria. For example, they have to predict the rate of aging, monitor a basic process
that underlies the aging process, be able to be tested repeatedly without harming the person. In addition, biomarkers have to be indicators of biological processes, pathogenic processes or pharmacological responses to therapeutic intervention. It is considered that the telomere length is the weak biomarker (with poor predictive accuracy), and there is currently no reliable biomarker that meets all the necessary criteria.
In this paper we point to some errors in recent paper by Asyaban et al. in which they devise an exact schedulability test. These errors are critical for the correct operation of the algorithm and they should be corrected.
The traffic density is a basic characteristic of marine traffic for some navigational area. In the case of narrow channels such as Strait of Split (Splitska vrata), apart from the traffic density, the number of simultaneous ship passages is also important as well as ships characteristics. Based on such data, additional navigational safety guidelines and regulations may be planned for the observed area. The purpose of this research is to determine the number of simultaneous ship passages via Strait of Split for a certain period of time. Collected AIS data in SPNMEA format was decoded by AIS Decoder online program to csv file. For five randomly selected days in the summer period, based on AIS data, the number of simultaneous ship passages was determined and ships information presented. http://www.transnav.eu the International Journal on Marine Navigation and Safety of Sea Transportation Volume 12 Number 4
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