Background: Dysferlin mutations cause progressive muscular dystrophies with strong inflammation, yet its function in immune cells is unclear.Results: Dysferlin forms a protein complex with focal adhesion proteins, and its loss in monocytes results in deregulated adhesion. Conclusion: Dysferlin is involved in regulating cellular interactions in human monocytes. Significance: Dysferlin dysfunction in monocytes may contribute to pathology in dysferlinopathy.

This study conducted a comparative evaluation of two bearingless cross-flow fan designs for applications in deep ultraviolet lithography excimer lasers, where maximizing the speed and power of the fan has a direct influence on the throughput and scanning speed of these devices. Using bearingless motor technology enables a combined generation of bearing force and drive torque and leads to a compact, hermetically sealed, and conveniently maintainable drive system. With identical bearingless motors on both rotor sides, it is possible to drive the cross-flow fan symmetrically to high rotational speeds at low torsional loads. The rotor prototypes were optimised, analysed, and pushed to high-speed operation and evaluated with respect to their rotor dynamic and fluid dynamic performance using finite element methods and experimental measurements. For both prototypes, successful numerical studies were performed, where a modal analysis enabled theoretical predictions of expected resonance frequencies, and a CFD analysis visualised local flow effects and provided cross-flow fan design comparisons. A stable operation of up to 12,000 rpm and 5500 rpm was accomplished for the two elaborated designs.

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This work presents a general and unified theory describing block copolymer selfassembly in the presence of free surfaces and nanoparticles in the context of Self-Consistent Filed Theory. Specifically, the derived theory applies to free and tethered polymer chains, nanoparticles of any shape, arbitrary non-uniform surface energies and grafting densities, and takes into account a possible formation of triple-junction points (e.g., polymer-air-substrate). One of the main ingredients of the proposed theory is a simple procedure for a consistent imposition of boundary conditions on surfaces with non-zero surface energies and/or non-zero grafting densities that results in singularityfree pressure-like fields, which is crucial for the calculation of forces. The generality of the theory is demonstrated using several representative examples such as the meniscus