Conflito de interesses: NãoContribuição dos autores: MVG coleta, tabulação, delineamento do estudo, discussão dos achados, etapas de execução e elaboração e redação do manuscrito. ISMI coleta e tabulação. RSJ orientação do projeto e delineamento do estudo. VCBG delineamento do estudo. Contato para correspondência: Mariana Vidotti Grandizoli E-mail: mariana.vidotti@hotmail. Descritores: Esperança; Ansiedade; Depressão; Neoplasias. Abstract Introduction:The hope of patients with malignant neoplasm plays a crucial role because it helps to resolve the difficulties which they deal with. These patients experience great changes, once this disease can result in emotional suffering. Objective: The aim of this research was to identify and correlate the indicators of hope, anxiety and depression of patients undergoing on cancer treatment. Patients and Methods: This is a cross-sectional, descriptive research involving individuals undergoing cancer treatment at the Cancer Institute and Hospital de Base in the city of São José do Rio Preto, inland of São Paulo State. Three instruments were answered by the participants: a) a sociodemographic questionnaire; b) The Hospital Anxiety and Depression Scale, and c) Herth's scale of hope. Results: The study sample was composed of 118 patients. Participants' mean age was 55.11 ± 13,34, with female prevalence. Regarding the clinical characteristics, there was a higher percentage of breast cancer (28%) and 54% of the participants presented cases of metastasis. The levels of hope presented an average of 39.6, anxiety 5.36 ± 3,66, and depression 5.82 ± 4,12. In this sample, 27% of the patients presented indicative indexes of depression and 24% anxiety indexes. Of these, 13% of the participants had both anxiety and depression. There was also a significant negative correlation between hope, anxiety (p = 0.0001) and depression (p = 0.0001). Conclusion: The individuals presented high levels of hope, which is revealed as a possible factor to protect anxiety and depression.