Aims: To determine the recovery degree in pediatric patients with antecedent severe traumatic brain injury. Study Design: Prospective, analytical and relational. Place and Duration of Study: Pediatrics Intensive Care Area of ​​the “Hospital para el Niño Poblano” from March 2014 to February 2015. Methodology: Patients aged 2 to 192 months, both sexes, with antecedent severe traumatic brain injury. The degree of recovery was determined with the Glasgow Outcome Score (GOS) at hospital discharge and one year after. Descriptive and inferential statistics were used data analysis. Results: The study consisted of 23 patients, of which 69.56% were men. The mean age was 73.17±50.33 months. The predominant age group was middle childhood (34.78%). The main mechanism of injury was run over by a vehicle (39.13%). The group of toddler remained hospitalized for 17.50±8.58 days. Moreover, GOS at hospital discharge (p=0.391) and at one year (p=0.789) was not associated with sex. Additionally, an association of GOS at hospital discharge was found with GOS at one year of care (p=0.003), with greater improvement being observed, in those cases with less initial damage brain. Conclusion: The degree of recovery at one year after hospital discharge in pediatric patients with antecedent severe traumatic brain injury is associated with the degree of recovery at hospital discharge. Middle childhood, being the group at greatest risk. The complications can reduce the recovery of the patient. Rehabilitation therapy provided by the public health services and the family is of vital importance.

Aims: To describe an infant presenting with miliary tuberculosis with cutaneous affectations and SARS-CoV-2 coinfection. Presentation of Case: 10 month old boy, with incomplete vaccination. Low Socio-economic status. The parents indicated, that lesion began with a single small, erythematous, non-pruritic, papule-type skin lesion on the left side of the infralabial region, with no other constitutional. During the following three months, the lesions became generalized. On June 23, 2020, he was admitted to the “Hospital para el Niño Poblano” in emergency area with mild malnutrition, lethargic state, fluid and electrolyte imbalance, metabolic acidosis, oral candidiasis, and septic shock, requiring endotracheal intubation. Besides, innumerable acid fast bacilli in skin biopsy and bronchial aspirate with diagnosis cutaneous TB was, identified. Immunodeficiency based on immunoglobulin profile and T and B cell markers. RT-PCR was performed for SARS-CoV-2 in bronchial aspirate, with a positive result. On June 25, 2020 died of cardiorespiratory arrest, secondary to septic shock and cutaneous tuberculosis. Discussion: Miliary TB in infants is difficult to diagnose in addition the cutaneous manifestation has added onto the long list of differentials, and downplay others, generating inappropriate and delayed treatment. Additionally, SARS-CoV-2 can intensify the clinical manifestations of miliary tuberculosis and directly influencing the mortality of this type of patients. Conclusion: The case described is rare, which reveals the importance to perform a differentiated diagnosis, considering Socio-economic and epidemiological context mainly in the first level of care. It is recommended to continue with research in order to generate information on the possible clinical pictures.