Background We validated the new European Organisation for Research and Treatment of Cancer Quality of Life Head and Neck Module (EORTC QLQ‐HN43). Methods We enrolled 812 patients with head and neck cancer from 18 countries. Group 1 completed the questionnaire before therapy, and 3 and 6 months later. In group 2 (survivors), we determined test–retest reliability using intraclass correlation coefficients (ICC). Internal consistency was assessed using Cronbach's Alpha, the scale structure with confirmatory factor analysis, and discriminant validity with known‐group comparisons. Results Cronbach's alpha was >0.70 in 10 of the 12 multi‐item scales. All standardized factor loadings exceeded 0.40. The ICC was >0.70 in all but two scales. Differences in scale scores between known‐groups were >10 points in 17 of the 19 scales. Sensitivity to change was found to be sufficient in 18 scales. Conclusions Evidence supports the reliability and validity of the EORTC QLQ‐HN43 as a measure of quality of life.

Purpose Surgical complications such as hypoparathyroidism (HPT) or vocal cord palsy are seldom assessed when the quality of life (QOL) in thyroid cancer patients is investigated. The aim of this study was to measure the QOL difference in thyroid cancer survivors with and without HPT. Methods Participants for this analysis were enrolled in 13 countries from a study which pilot-tested a thyroid cancer specific QOL instrument. They were included if they had been diagnosed with thyroid cancer at least nine months previously. QOL was measured using the EORTC QLQ-C30 and some items on HPT symptoms (e.g. tingling in fingers or toes). HPT status and other clinical data were extracted from the patients’ medical charts. Comparisons of QOL domains between patients with and without HPT were performed using Mann-Whitney U test. The occurrence of HPT-related symptoms was compared using Chi-Square-Tests. Multiple ordinal regression analysis was performed to evaluate factors which might have an impact on QOL. Results Eighty-nine patients participated in this study, 17 of whom were considered to have HPT. Patients in the HPT group reported significantly reduced QOL in nine of the 15 scales of the EORTC QLQ-C30 compared to patients without HPT. Regression analysis showed that HPT was independently negatively associated with various scales of the QLQ-C30. Both groups showed a high prevalence of typical HPT symptoms. Conclusion Thyroid cancer patients with HPT report significantly impaired QOL compared to thyroid cancer survivors without HPT. The assessment of HPT should be considered when measuring QOL in thyroid cancer patients.

BACKGROUND. Kinesiology Taping (KT) is being increasingly more often used in musculoskeletal rehabilitation. The aim of the study was to assess the effect of Kinesiology Taping on rehabilitation outcomes in patients following anterior cruciate ligament (ACL) reconstruction. MATERIALS AND METHODS. The study enrolled 26 patients (16 women and 10 men) aged between 20 and 41 years. The patients were randomly divided into two groups: an experimental group (Group 1), which received Kinesiology Taping, and a control group (Group 2), which followed the same rehabilitation protocol except for KT. Student's t test with a minimum significance level at p<0.05 was used for statistical analysis. RESULTS. All participants demonstrated a significant improvement in the range of knee flexion and extension in the affected limb as soon as the end of the first week of rehabilitation (p˂0.001). This tendency persisted in the following weeks until Day 28. Thigh measurements revealed a faster increase in thigh circumference in Group 1. Significant swelling reduction was found among patients from the experimental group at all consecutive measurements. The greatest difference (p<0.001) was noted at the beginning of the rehabilitation. After 28 days of rehabilitation, pain intensity and pain frequency had significantly decreased in all patients (p<0.001). Patients from the control group used analgesics significantly more often. CONCLUSIONS. 1. The use of KT contributed to a faster improvement of the range of knee motion, reduction of oedema and greater improvement in thigh circumference. 2. A similar reduction in pain intensity was observed in all patients. However, pain significantly less often forced patients from the experimental group to use analgesics or reduced their activity.

Objective Health‐related quality of life (HRQoL) concerns of adolescents and young adults (AYAs) aged 14–25 years were compared with those of older adults (26–60 years) with cancer. Methods AYAs and older adults receiving curative intent treatment or supportive palliative care for cancer were recruited from eight research centres across Europe. Participants used a rating scale to score the relevance and importance of a list of 77 issues covering 10 areas of HRQoL concern: symptoms; activity restrictions; social; emotional; body image; self‐appraisals; outlook on life; lifestyle; treatment‐related and life beyond treatment. Results HRQoL issues were reviewed by 33 AYAs and 25 older adults. Several issues were recognised as relevant and important across all age groups: symptoms, emotional impact, outlook on life, lifestyle and treatment‐related. A number of issues were more relevant or important to AYAs including interrupted education, greater motivation to achieve academic goals, increased maturity, boredom, fertility and change in living situation. Conclusion While there is overlap in several of the HRQoL concerns across the age span, it is important that HRQoL measures used with AYAs capture the diverse and unique psychosocial aspects of this developmental stage.

Purpose The purpose of the study was to analyze the total prevalence, morphologic, and morphometric characteristics of the pterygospinous (PS) bar and its gender and ethnic differences among populations. PS bar is an ossified anatomic structure stretching between the posterior margin of the lateral pterygoid lamina to the angular spine of the undersurface of the sphenoid, with potential clinical implications. There is no consensus in the literature on its prevalence, morphologic, and morphometric characteristics. Methods A thorough search of databases was conducted. Data on the prevalence, morphology, i.e., ossification type (complete and incomplete), side, gender, laterality, and morphometrics, of the PS bar were extracted and pooled into a meta-analysis. Results A total of 35 studies (n = 14,047 subjects) were analyzed. The overall pooled prevalence of a complete PS bar was 4.4% (95% CI 3.7-5.1), while the overall pooled prevalence of an incomplete PS bar was significantly higher (11.6% [95% CI 8.5-15.2]). A complete PS bar was more prevalent among males and was more commonly unilaterally, on the left side. Conclusion The overall prevalence of PS bar is quite common. It could be of importance for clinicians who should consider its potential presence when planning surgical approaches to the retropharyngeal and parapharyngeal space.