Introduction. Among infectious agents associated with provision of medical care, resistant ones to disinfectants from various chemical groups are more often met. In this regard, disinfection measures carried out in a medical facility are not always effective enough. Material and methods. 9 strains of microorganisms were selected for research (Klebsiella pneumoniae -2 pcs., Enterococcus faecalis, Staphylococcus warneri, Serratia rubidaea, Staphylococcus sciuri, Enterobacter cloacae, Acinetobacter baumannii, Enterococcus faecium - per 1 pcs.), isolated from the objects of hospital environment in operating unit, intensive care and trauma units, as well as 5 samples of disinfectants from different chemical groups (on the basis of quaternary ammonium salt, tertiary amine and polyhexamethyleneguanidine; on the basis of sodium percarbonate with activator; on the basis of hydrogen peroxide and didecyldimethylammonium chloride; in the form of tablets on the basis of sodium salt sodium dichloroisocyanurate acid), used in the specified divisions of medical facities. The studies were performed in accordance with the methodology set out in methodology instructions MU 3.5.1.3439-17 “Assessment of sensitivity to disinfectants of microorganisms circulating in medical organizations.” Results. When conducting chemical-analytical studies of samples of disinfectants 4 samples out of 5 were found to have inconsistencies in one or another quality indices. The analysis of instructions on application of disinfectants 4 means from 5 were showed to have unreasonably underestimated modes of application. According to the results of the evaluation of the sensitivity of microorganisms to disinfectants, the majority of isolated microorganisms was found to have resistance to the studied disinfectants Conclusion. Based on the results of the study of sensitivity of microorganisms to disinfectants, a new tactic for improving disinfection measures is proposed for medical facilities: rotation of disinfectants and an enhanced system of microbiological monitoring of the sensitivity of microorganisms to disinfectants

Background. The pandemic of the new coronavirus infection COVID-19 determines the relevance of conducting a study of the gender age structure of hospitalized and deceased among the population of Moscow on the example of one of the city clinical hospitals in 2020 and 2021. The aim of the work is to identify the patterns of the epidemic process of COVID-19 in connection with the gender and age characteristics of hospitalized adults and to establish the sex and age groups most susceptible to hospitalization and mortality from COVID-19. Materials and methods. The analysis of the structure of hospitalized and deceased from COVID-19 in the context of their gender and age composition was carried out. The data of the statistical accounting form F-60u/lech "Journal of infectious diseases" of adults hospitalized in one of the city clinical hospitals of Moscow in 2020 and 2021 were used. Data processing was carried out by a set of standard statistical methods. To identify the true risk groups for hospitalization and mortality, a statistical correction of the sex and age composition of the population of Moscow was used. Results and discussion. Using standard statistical methods in combination with the use of statistical correction of sex and age composition, data on the true risk groups for hospitalization and mortality among the population of Moscow in 2020 and 2021 were obtained. Conclusion. The results obtained in our independent study on the true risk groups for hospitalization and mortality among the population of Moscow complement and introduce new knowledge about the true risk groups for hospitalization and mortality in COVID-19. The patterns identified in this epidemiological analysis are an important component of epidemiological surveillance for making managerial decisions to prevent the spread of SARS-CoV-2 and planning for the provision of inpatient medical care to established gender and age risk groups.

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Introduction. Among infectious agents associated with provision of medical care, resistant ones to disinfectants from various chemical groups are more often met. In this regard, disinfection measures carried out in a medical facility are not always effective enough. Material and methods. 9 strains of microorganisms were selected for research (Klebsiella pneumoniae -2 pcs., Enterococcus faecalis, Staphylococcus warneri, Serratia rubidaea, Staphylococcus sciuri, Enterobacter cloacae, Acinetobacter baumannii, Enterococcus faecium - per 1 pcs.), isolated from the objects of hospital environment in operating unit, intensive care and trauma units, as well as 5 samples of disinfectants from different chemical groups (on the basis of quaternary ammonium salt, tertiary amine and polyhexamethyleneguanidine; on the basis of sodium percarbonate with activator; on the basis of hydrogen peroxide and didecyldimethylammonium chloride; in the form of tablets on the basis of sodium salt sodium dichloroisocyanurate acid), used in the specified divisions of medical facities. The studies were performed in accordance with the methodology set out in methodology instructions MU 3.5.1.3439-17 “Assessment of sensitivity to disinfectants of microorganisms circulating in medical organizations.” Results. When conducting chemical-analytical studies of samples of disinfectants 4 samples out of 5 were found to have inconsistencies in one or another quality indices. The analysis of instructions on application of disinfectants 4 means from 5 were showed to have unreasonably underestimated modes of application. According to the results of the evaluation of the sensitivity of microorganisms to disinfectants, the majority of isolated microorganisms was found to have resistance to the studied disinfectants Conclusion. Based on the results of the study of sensitivity of microorganisms to disinfectants, a new tactic for improving disinfection measures is proposed for medical facilities: rotation of disinfectants and an enhanced system of microbiological monitoring of the sensitivity of microorganisms to disinfectants